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5m05

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Current revision (18:18, 1 November 2023) (edit) (undo)
 
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<StructureSection load='5m05' size='340' side='right'caption='[[5m05]], [[Resolution|resolution]] 2.67&Aring;' scene=''>
<StructureSection load='5m05' size='340' side='right'caption='[[5m05]], [[Resolution|resolution]] 2.67&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5m05]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Chick Chick]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M05 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5M05 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5m05]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M05 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5M05 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=52E:4-{[(2-CHLORO-3-FLUOROBENZYL)CARBAMOYL](METHYL)AMINO}-3,4-DIDEOXY-5-O-(ISOQUINOLIN-3-YLCARBAMOYL)-D-ERYTHRO-PENTITOL'>52E</scene>, <scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.675&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MYH11 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9031 CHICK])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=52E:4-{[(2-CHLORO-3-FLUOROBENZYL)CARBAMOYL](METHYL)AMINO}-3,4-DIDEOXY-5-O-(ISOQUINOLIN-3-YLCARBAMOYL)-D-ERYTHRO-PENTITOL'>52E</scene>, <scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5m05 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m05 OCA], [http://pdbe.org/5m05 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5m05 RCSB], [http://www.ebi.ac.uk/pdbsum/5m05 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5m05 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5m05 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m05 OCA], [https://pdbe.org/5m05 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5m05 RCSB], [https://www.ebi.ac.uk/pdbsum/5m05 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5m05 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/MYH11_CHICK MYH11_CHICK]] Muscle contraction.
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[https://www.uniprot.org/uniprot/MYH11_CHICK MYH11_CHICK] Muscle contraction.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Chick]]
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[[Category: Gallus gallus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Hartman, J]]
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[[Category: Hartman J]]
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[[Category: Houdusse, A]]
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[[Category: Houdusse A]]
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[[Category: Sirigu, S]]
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[[Category: Sirigu S]]
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[[Category: Motor protein]]
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[[Category: Myosin inhibitor]]
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Current revision

Chicken smooth muscle myosin motor domain co-crystallized with the specific CK-571 inhibitor, MgADP form

PDB ID 5m05

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