6yt2

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (13:34, 24 January 2024) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='6yt2' size='340' side='right'caption='[[6yt2]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='6yt2' size='340' side='right'caption='[[6yt2]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[6yt2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6YT2 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6YT2 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[6yt2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6YT2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6YT2 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C15:N-DODECYL-N,N-DIMETHYL-3-AMMONIO-1-PROPANESULFONATE'>C15</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PJW:benzo[b][1]benziodole'>PJW</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MAOB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C15:N-DODECYL-N,N-DIMETHYL-3-AMMONIO-1-PROPANESULFONATE'>C15</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PJW:benzo[b][1]benziodole'>PJW</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Monoamine_oxidase Monoamine oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.3.4 1.4.3.4] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6yt2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6yt2 OCA], [https://pdbe.org/6yt2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6yt2 RCSB], [https://www.ebi.ac.uk/pdbsum/6yt2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6yt2 ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6yt2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6yt2 OCA], [http://pdbe.org/6yt2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6yt2 RCSB], [http://www.ebi.ac.uk/pdbsum/6yt2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6yt2 ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/AOFB_HUMAN AOFB_HUMAN]] Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine.
+
[https://www.uniprot.org/uniprot/AOFB_HUMAN AOFB_HUMAN] Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 20: Line 19:
</div>
</div>
<div class="pdbe-citations 6yt2" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6yt2" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[Monoamine oxidase|Monoamine oxidase]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Human]]
+
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Monoamine oxidase]]
+
[[Category: Binda C]]
-
[[Category: Binda, C]]
+
[[Category: Iacovino LG]]
-
[[Category: Iacovino, L G]]
+
[[Category: Mai A]]
-
[[Category: Mai, A]]
+
[[Category: Mattevi A]]
-
[[Category: Mattevi, A]]
+
[[Category: Reis J]]
-
[[Category: Reis, J]]
+
-
[[Category: Drug target]]
+
-
[[Category: Flavin]]
+
-
[[Category: Flavoprotein]]
+
-
[[Category: Mitochondrial membrane]]
+
-
[[Category: Neurodegeneration]]
+
-
[[Category: Ro]]
+

Current revision

Crystal Structure of human monoamine oxidase B in complex with Diphenylene iodonium (DPI)

PDB ID 6yt2

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/6yt2"
Personal tools