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5mbl

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Current revision (18:37, 1 November 2023) (edit) (undo)
 
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<StructureSection load='5mbl' size='340' side='right'caption='[[5mbl]], [[Resolution|resolution]] 1.81&Aring;' scene=''>
<StructureSection load='5mbl' size='340' side='right'caption='[[5mbl]], [[Resolution|resolution]] 1.81&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5mbl]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MBL OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5MBL FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5mbl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MBL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5MBL FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.81&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SCH:S-METHYL-THIO-CYSTEINE'>SCH</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SCH:S-METHYL-THIO-CYSTEINE'>SCH</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_B Cathepsin B], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.1 3.4.22.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5mbl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mbl OCA], [https://pdbe.org/5mbl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5mbl RCSB], [https://www.ebi.ac.uk/pdbsum/5mbl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5mbl ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5mbl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mbl OCA], [http://pdbe.org/5mbl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mbl RCSB], [http://www.ebi.ac.uk/pdbsum/5mbl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mbl ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CATB_HUMAN CATB_HUMAN]] Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.
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[https://www.uniprot.org/uniprot/CATB_HUMAN CATB_HUMAN] Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Cathepsin B]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Kramer, L]]
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[[Category: Synthetic construct]]
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[[Category: Renko, M]]
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[[Category: Kramer L]]
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[[Category: Turk, B]]
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[[Category: Renko M]]
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[[Category: Turk, D]]
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[[Category: Turk B]]
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[[Category: Complex]]
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[[Category: Turk D]]
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[[Category: Darpin]]
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[[Category: Hydrolase]]
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[[Category: Protease]]
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Current revision

Cathepsin B in complex with DARPin 81

PDB ID 5mbl

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