Indole-3-glycerol phosphate synthase

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*Indole-3-glycerol phosphate synthase
*Indole-3-glycerol phosphate synthase
 +
**[[1ox4]], [[1ox6]] – yIGPS HISHF amidotransferase+cyclase domains 1-552 + Ni + PP - yeast<br />
**[[1igs]], [[3tc6]], [[3tc7]] – SsIGPS + PO4 – ''Sulfolobus solfataricus'' <br />
**[[1igs]], [[3tc6]], [[3tc7]] – SsIGPS + PO4 – ''Sulfolobus solfataricus'' <br />
**[[5aou]] – SsIGPS (mutant) + PO4 <br />
**[[5aou]] – SsIGPS (mutant) + PO4 <br />
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**[[1jul]] – SsIGPS <br />
**[[1jul]] – SsIGPS <br />
**[[4a2r]], [[4a2s]], [[4a29]] - SsIGPS TIM-barrel fold (mutant) <br />
**[[4a2r]], [[4a2s]], [[4a29]] - SsIGPS TIM-barrel fold (mutant) <br />
-
**[[1i4n]] – TmIGPS + SO4 – ''Thermotoga maritima''<br />
+
**[[1j5t]], [[2w6r]] – TmIGPS – ''Thermotoga maritima'' <br />
-
**[[1j5t]] – TmIGPS <br />
+
**[[1i4n]] – TmIGPS + SO4 <br />
 +
**[[4j9j]] – TmIGPS subunit HISF (mutant) <br />
 +
**[[1vh7]], [[2a0n]] – TmIGPS subunit HISF + PO4 <br />
 +
**[[4fx7]], [[5tql]], [[6vdg]] – TmIGPS subunit HISF (mutant) + PO4 <br />
 +
**[[3og3]] – TmIGPS subunit HISF (mutant) + SO4 <br />
 +
**[[3zr4]] – TmIGPS subunits HISF+HISH + Gln <br />
 +
**[[6ymu]] – TmIGPS subunits HISF+HISH + Phe derivative <br />
 +
**[[6rtz]], [[6ru0]] – TmIGPS subunits HISF+HISH + PO4 <br />
 +
**[[2wjz]] – TmIGPS subunits HISF+HISH (mutant) + PO4 <br />
**[[1vc4]] – IGPS + SO4 – ''Thermus thermophilus''<br />
**[[1vc4]] – IGPS + SO4 – ''Thermus thermophilus''<br />
**[[3qja]] – MtGPS + SO4 – ''Mycobacterium tuberculosis''<br />
**[[3qja]] – MtGPS + SO4 – ''Mycobacterium tuberculosis''<br />
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**[[3tsm]] – IGPS + SO4 – ''Brucella melitensis''<br />
**[[3tsm]] – IGPS + SO4 – ''Brucella melitensis''<br />
**[[6bma]] – IGPS + PO4 – ''Campylobacter jejuni''<br />
**[[6bma]] – IGPS + PO4 – ''Campylobacter jejuni''<br />
 +
**[[4gud]] – IGPS subunit HISH – ''Vibrio cholerae'' <br />
*IGPS complex with reactants or derivatives
*IGPS complex with reactants or derivatives
 +
**[[1ox4]] – yIGPS HISHF amidotransferase+cyclase domains (mutant) + Ni + imidazole derivative<br />
**[[1a53]] – SsIGPS + IGP <br />
**[[1a53]] – SsIGPS + IGP <br />
**[[1lbf]], [[1lbl]] – SsIGPS + CDRP <br />
**[[1lbf]], [[1lbl]] – SsIGPS + CDRP <br />
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**[[3t78]] – MtIGPS + fluoroanthranilate<br />
**[[3t78]] – MtIGPS + fluoroanthranilate<br />
**[[1jcm]] – EcIGPS N terminal + CDRP derivative – ''Escherichia coli''<br />
**[[1jcm]] – EcIGPS N terminal + CDRP derivative – ''Escherichia coli''<br />
 +
**[[4ewn]] – TmIGPS subunit HISF (mutant) + RCDRP <br />
}}
}}
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 07:50, 24 August 2020

Structure of IGPS complex with IGP (PDB entry 1a53)

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3D structures of IGPS

Updated on 24-August-2020

References

  1. ↑ Creighton TE, Yanofsky C. Indole-3-glycerol phosphate synthetase of Escherichia coli, an enzyme of the tryptophan operon. J Biol Chem. 1966 Oct 25;241(20):4616-24. PMID:5332729
  2. ↑ Hennig M, Darimont BD, Jansonius JN, Kirschner K. The catalytic mechanism of indole-3-glycerol phosphate synthase: crystal structures of complexes of the enzyme from Sulfolobus solfataricus with substrate analogue, substrate, and product. J Mol Biol. 2002 Jun 7;319(3):757-66. PMID:12054868 doi:http://dx.doi.org/10.1016/S0022-2836(02)00378-9

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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