5ndx

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Current revision (12:49, 15 November 2023) (edit) (undo)
 
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<StructureSection load='5ndx' size='340' side='right'caption='[[5ndx]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='5ndx' size='340' side='right'caption='[[5ndx]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5ndx]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NDX OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5NDX FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5ndx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhizobium_leguminosarum_bv._trifolii Rhizobium leguminosarum bv. trifolii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NDX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5NDX FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8U8:(2~{R},3~{S},4~{S},5~{R},6~{S})-6-(4-methyl-2-oxidanylidene-chromen-7-yl)oxy-3,4,5-tris(oxidanyl)oxane-2-carboxylic+acid'>8U8</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5ndx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ndx OCA], [http://pdbe.org/5ndx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ndx RCSB], [http://www.ebi.ac.uk/pdbsum/5ndx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ndx ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8U8:(2~{R},3~{S},4~{S},5~{R},6~{S})-6-(4-methyl-2-oxidanylidene-chromen-7-yl)oxy-3,4,5-tris(oxidanyl)oxane-2-carboxylic+acid'>8U8</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ndx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ndx OCA], [https://pdbe.org/5ndx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ndx RCSB], [https://www.ebi.ac.uk/pdbsum/5ndx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ndx ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/A0A1B8R7L2_RHILT A0A1B8R7L2_RHILT]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Castro-Lopez, J]]
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[[Category: Rhizobium leguminosarum bv. trifolii]]
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[[Category: Hurtado-Guerrero, R]]
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[[Category: Castro-Lopez J]]
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[[Category: Jimenez-Garcia, M J]]
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[[Category: Hurtado-Guerrero R]]
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[[Category: Millan, C]]
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[[Category: Jimenez-Garcia MJ]]
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[[Category: Nieto, P]]
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[[Category: Millan C]]
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[[Category: Raich, L]]
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[[Category: Nieto P]]
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[[Category: Rovira, C]]
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[[Category: Raich L]]
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[[Category: Uson, I]]
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[[Category: Rovira C]]
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[[Category: Valero-Gonzalez, J]]
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[[Category: Uson I]]
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[[Category: Catalytic itinerary]]
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[[Category: Valero-Gonzalez J]]
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[[Category: Catalytic mechanism]]
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[[Category: Human a-l-iduronidase]]
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[[Category: Hydrolase]]
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[[Category: Iduronidase]]
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[[Category: Mucopolysaccharidosis i]]
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[[Category: N-glycosylation site]]
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[[Category: Reaction coordinate]]
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[[Category: Rhizobium leguminosarum]]
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Current revision

The bacterial orthologue of Human a-L-iduronidase does not need N-glycan post-translational modifications to be catalytically competent: Crystallography and QM/MM insights into Mucopolysaccharidosis I

PDB ID 5ndx

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