6zjn

==Respiratory complex I from Thermus thermophilus, NADH dataset, minor state==

<StructureSection load='6zjn' size='340' side='right'caption='[[6zjn]], [[Resolution|resolution]] 6.10&Aring;' scene=''>

<table><tr><td colspan='2'>[[6zjn]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ZJN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ZJN FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 6.1&#8491;</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zjn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zjn OCA], [https://pdbe.org/6zjn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zjn RCSB], [https://www.ebi.ac.uk/pdbsum/6zjn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zjn ProSAT]</span></td></tr>

== Function ==

[https://www.uniprot.org/uniprot/NQO6_THET8 NQO6_THET8] NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient required for the synthesis of ATP.[HAMAP-Rule:MF_01356]

==See Also==

*[[NADH-quinone oxidoreductase|NADH-quinone oxidoreductase]]

[[Category: Thermus thermophilus]]

[[Category: Tambalo M]]