7bw0

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Current revision (10:49, 27 March 2024) (edit) (undo)
 
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====
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==Active human TGR5 complex with a synthetic agonist 23H==
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<StructureSection load='7bw0' size='340' side='right'caption='[[7bw0]]' scene=''>
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<StructureSection load='7bw0' size='340' side='right'caption='[[7bw0]], [[Resolution|resolution]] 3.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7bw0]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus], [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli], [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus] and [https://en.wikipedia.org/wiki/Vicugna_pacos Vicugna pacos]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BW0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7BW0 FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=7bw0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7bw0 OCA], [http://pdbe.org/7bw0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7bw0 RCSB], [http://www.ebi.ac.uk/pdbsum/7bw0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=7bw0 ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.9&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7bw0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7bw0 OCA], [https://pdbe.org/7bw0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7bw0 RCSB], [https://www.ebi.ac.uk/pdbsum/7bw0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7bw0 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/C562_ECOLX C562_ECOLX] Electron-transport protein of unknown function.[https://www.uniprot.org/uniprot/GPBAR_HUMAN GPBAR_HUMAN] Receptor for bile acid. Bile acid-binding induces its internalization, activation of extracellular signal-regulated kinase and intracellular cAMP production. May be involved in the suppression of macrophage functions by bile acids.<ref>PMID:12419312</ref> <ref>PMID:12524422</ref>
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==See Also==
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*[[Transducin 3D structures|Transducin 3D structures]]
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bos taurus]]
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[[Category: Escherichia coli]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Z-disk]]
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[[Category: Rattus norvegicus]]
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[[Category: Vicugna pacos]]
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[[Category: Chen G]]
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[[Category: Chen Q]]
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[[Category: Hu HL]]
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[[Category: Ren RB]]
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[[Category: Wang XK]]

Current revision

Active human TGR5 complex with a synthetic agonist 23H

PDB ID 7bw0

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OCA

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