Pertussis toxin

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== 3D Structures of Pertussis toxin ==
== 3D Structures of Pertussis toxin ==
-
[[1prt]] – BpPT - ''Bordetella pertussis''<br />
+
**[[1prt]] – BpPT - ''Bordetella pertussis''<br />
-
[[1pto]] – BpPT + galactose<br />
+
**[[1pto]] – BpPT + galactose<br />
-
[[1bcp]] – BpPT + ATP<br />
+
**[[1bcp]] – BpPT + ATP<br />
-
[[6ro0]] – BpPT 1,2,5 subunits + islet-activating protein S2 + islet-activating protein S3 + islet-activating protein S4<br />
+
**[[6ro0]] – BpPT 1,2,5 subunits + islet-activating protein S2 + islet-activating protein S3 + islet-activating protein S4<br />
 +
**[[7ski]] – BpPT subunit 1 + phenanthridine derivative<br />
 +
**[[7sky]] – BpPT subunit 1 + NAD<br />
 +
**[[7u6z]] – BpPT subunit 1 (mutant) + NAD<br />
 +
**[[7sne]] – BpPT subunit 1 + BaAD<br />
 +
**[[7skk]] – BpPT subunit 1 + ADPR + nicotinamide<br />
-
'''Pertactin'''
+
*Pertussis-like toxin
-
[[1dab]] - BpPer<br />
+
**[[4z9d]] – EcPLT subunit A (mutant) – ''Escherichia coli''<br />
-
[[2iou]] - Per extracellular domain + major tropism determinant - ''Bordetella bronchiseptica''<br />
+
**[[4z9c]] – EcPLT subunits A,B <br />
 +
**[[7k7h]] – SaPLT subunits A,B + antibody – ''Salmonella enterica'' – Cryo EM<br />
 +
 
 +
*'''Pertactin'''
 +
 
 +
**[[1dab]] - BpPer<br />
 +
**[[2iou]] - Per extracellular domain + major tropism determinant - ''Bordetella bronchiseptica''<br />
 +
 
 +
]]
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 10:16, 22 August 2023

Pertussis toxin (PDB entry 1prt)

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3D Structures of Pertussis toxin

    • 1prt – BpPT - Bordetella pertussis
    • 1pto – BpPT + galactose
    • 1bcp – BpPT + ATP
    • 6ro0 – BpPT 1,2,5 subunits + islet-activating protein S2 + islet-activating protein S3 + islet-activating protein S4
    • 7ski – BpPT subunit 1 + phenanthridine derivative
    • 7sky – BpPT subunit 1 + NAD
    • 7u6z – BpPT subunit 1 (mutant) + NAD
    • 7sne – BpPT subunit 1 + BaAD
    • 7skk – BpPT subunit 1 + ADPR + nicotinamide
  • Pertussis-like toxin
    • 4z9d – EcPLT subunit A (mutant) – Escherichia coli
    • 4z9c – EcPLT subunits A,B
    • 7k7h – SaPLT subunits A,B + antibody – Salmonella enterica – Cryo EM
  • Pertactin
    • 1dab - BpPer
    • 2iou - Per extracellular domain + major tropism determinant - Bordetella bronchiseptica

]]

References

  1. Carbonetti NH, Artamonova GV, Andreasen C, Bushar N. Pertussis toxin and adenylate cyclase toxin provide a one-two punch for establishment of Bordetella pertussis infection of the respiratory tract. Infect Immun. 2005 May;73(5):2698-703. PMID:15845471 doi:http://dx.doi.org/10.1128/IAI.73.5.2698-2703.2005
  2. Connelly CE, Sun Y, Carbonetti NH. Pertussis toxin exacerbates and prolongs airway inflammatory responses during Bordetella pertussis infection. Infect Immun. 2012 Dec;80(12):4317-32. doi: 10.1128/IAI.00808-12. Epub 2012 Oct, 1. PMID:23027529 doi:http://dx.doi.org/10.1128/IAI.00808-12

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Michal Harel, Jonathan Tringali

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