5umy

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Current revision (13:30, 4 October 2023) (edit) (undo)
 
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<StructureSection load='5umy' size='340' side='right'caption='[[5umy]], [[Resolution|resolution]] 1.78&Aring;' scene=''>
<StructureSection load='5umy' size='340' side='right'caption='[[5umy]], [[Resolution|resolution]] 1.78&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5umy]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_sp._cb03234 Streptomyces sp. cb03234]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UMY OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5UMY FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5umy]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_sp._CB03234 Streptomyces sp. CB03234]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UMY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5UMY FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TNN:(1aS,11S,11aR,14Z,18R)-3,8,18-trihydroxy-11a-[(1R)-1-hydroxyethyl]-7-methoxy-11,11a-dihydro-4H-11,1a-hept[3]ene[1,5]diynonaphtho[2,3-h]oxireno[c]quinoline-4,9(10H)-dione'>TNN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.78&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">tnmS3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1703937 Streptomyces sp. CB03234])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TNN:(1aS,11S,11aR,14Z,18R)-3,8,18-trihydroxy-11a-[(1R)-1-hydroxyethyl]-7-methoxy-11,11a-dihydro-4H-11,1a-hept[3]ene[1,5]diynonaphtho[2,3-h]oxireno[c]quinoline-4,9(10H)-dione'>TNN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5umy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5umy OCA], [http://pdbe.org/5umy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5umy RCSB], [http://www.ebi.ac.uk/pdbsum/5umy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5umy ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5umy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5umy OCA], [https://pdbe.org/5umy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5umy RCSB], [https://www.ebi.ac.uk/pdbsum/5umy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5umy ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/A0A125SA29_9ACTN A0A125SA29_9ACTN]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Streptomyces sp. cb03234]]
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[[Category: Streptomyces sp. CB03234]]
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[[Category: Chang, C]]
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[[Category: Chang C]]
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[[Category: Chang, C Y]]
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[[Category: Chang CY]]
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[[Category: Joachimiak, A]]
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[[Category: Joachimiak A]]
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[[Category: Structural genomic]]
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[[Category: Nocek B]]
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[[Category: NatPro, Enzyme Discovery for Natural Product Biosynthesis]]
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[[Category: Phillips Jr GN]]
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[[Category: Nocek, B]]
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[[Category: Rudolf JD]]
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[[Category: Phillips, G N]]
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[[Category: SHen B]]
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[[Category: Rudolf, J D]]
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[[Category: SHen, B]]
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[[Category: Enzyme discovery for natural product biosynthesis]]
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[[Category: Glyoxalase/bleomycin resistance protein/dioxygenase superfamily]]
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[[Category: Lyase]]
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[[Category: Mcsg]]
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[[Category: Natpro]]
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[[Category: Psi-biology]]
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[[Category: Tiancimycin-binding protein]]
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Current revision

Crystal structure of TnmS3 in complex with tiancimycin

PDB ID 5umy

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