5qhj
From Proteopedia
(Difference between revisions)
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<StructureSection load='5qhj' size='340' side='right'caption='[[5qhj]], [[Resolution|resolution]] 1.68Å' scene=''> | <StructureSection load='5qhj' size='340' side='right'caption='[[5qhj]], [[Resolution|resolution]] 1.68Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5qhj]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QHJ OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[5qhj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QHJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5QHJ FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOV:( | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOV:(2S)-1-{[(2H-1,3-benzodioxol-5-yl)methyl]amino}propan-2-ol'>GOV</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FAM83B, C6orf143 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5qhj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qhj OCA], [https://pdbe.org/5qhj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5qhj RCSB], [https://www.ebi.ac.uk/pdbsum/5qhj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5qhj ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/FA83B_HUMAN FA83B_HUMAN]] Probable proto-oncogene that functions in the epidermal growth factor receptor/EGFR signaling pathway. May activate both the EGFR itself and downstream RAS/MAPK and PI3K/AKT/TOR signaling cascades.<ref>PMID:22886302</ref> <ref>PMID:23676467</ref> <ref>PMID:23912460</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Arrowsmith, C H]] | [[Category: Arrowsmith, C H]] | ||
Revision as of 10:11, 13 April 2022
PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human FAM83B in complex with FMOPL000709a
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Categories: Human | Large Structures | Arrowsmith, C H | Bountra, C | Bufton, J C | Bullock, A N | Collins, P | Delft, F von | Douangamath, A | Edwards, A | Fox, A E | Krojer, T | Pinkas, D M | Talon, R | Zhang, R | Duf1669 domain | Pandda | Protein binding | Sgc - diamond i04-1 fragment screening | Xchemexplorer
