6st7
From Proteopedia
(Difference between revisions)
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==Crystal Structure of Domain Swapped Trp Repressor V58I Variant with bound L-trp== | ==Crystal Structure of Domain Swapped Trp Repressor V58I Variant with bound L-trp== | ||
| - | <StructureSection load='6st7' size='340' side='right'caption='[[6st7]]' scene=''> | + | <StructureSection load='6st7' size='340' side='right'caption='[[6st7]], [[Resolution|resolution]] 2.45Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ST7 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6ST7 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[6st7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ST7 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6ST7 FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6st7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6st7 OCA], [http://pdbe.org/6st7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6st7 RCSB], [http://www.ebi.ac.uk/pdbsum/6st7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6st7 ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=TRP:TRYPTOPHAN'>TRP</scene></td></tr> |
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1mi7|1mi7]], [[1jhg|1jhg]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">trpR, rtrY, b4393, JW4356 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6st7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6st7 OCA], [http://pdbe.org/6st7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6st7 RCSB], [http://www.ebi.ac.uk/pdbsum/6st7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6st7 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/TRPR_ECOLI TRPR_ECOLI]] This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Ecoli]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Carey J]] | + | [[Category: Carey, J]] |
| - | [[Category: Drouard F]] | + | [[Category: Drouard, F]] |
| - | [[Category: Lawson | + | [[Category: Lawson, C L]] |
| - | [[Category: | + | [[Category: Leggio, L Lo]] |
| - | [[Category: | + | [[Category: Linse, S]] |
| - | [[Category: Schulz A]] | + | [[Category: Schulz, A]] |
| - | [[Category: Sprenger J]] | + | [[Category: Sprenger, J]] |
| - | [[Category: | + | [[Category: Wachenfeldt, C von]] |
| + | [[Category: Dna binding protein]] | ||
| + | [[Category: Domain swapping]] | ||
| + | [[Category: Hostal]] | ||
| + | [[Category: L-trp binding]] | ||
Revision as of 06:36, 7 October 2020
Crystal Structure of Domain Swapped Trp Repressor V58I Variant with bound L-trp
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