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5w87

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Current revision (14:08, 4 October 2023) (edit) (undo)
 
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<StructureSection load='5w87' size='340' side='right'caption='[[5w87]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='5w87' size='340' side='right'caption='[[5w87]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5w87]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5W87 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5W87 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5w87]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5W87 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5W87 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.199&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.2.26 2.3.2.26] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5w87 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5w87 OCA], [http://pdbe.org/5w87 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5w87 RCSB], [http://www.ebi.ac.uk/pdbsum/5w87 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5w87 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5w87 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5w87 OCA], [https://pdbe.org/5w87 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5w87 RCSB], [https://www.ebi.ac.uk/pdbsum/5w87 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5w87 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/HERC6_HUMAN HERC6_HUMAN]] E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
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[https://www.uniprot.org/uniprot/HERC6_HUMAN HERC6_HUMAN] E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Transferase]]
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[[Category: BELLESIS AG]]
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[[Category: BELLESIS, A G]]
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[[Category: ROYER WE]]
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[[Category: ROYER, W E]]
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[[Category: SPRATT DE]]
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[[Category: SPRATT, D E]]
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[[Category: WANG Y]]
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[[Category: WANG, Y]]
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[[Category: Antiviral activity]]
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[[Category: E3 ligase]]
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[[Category: Transferase-ligase complex]]
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Current revision

Crystal structure of the C-terminal lobe of the human HERC6 HECT domain

PDB ID 5w87

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