5wy3

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:19, 20 March 2024) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='5wy3' size='340' side='right'caption='[[5wy3]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
<StructureSection load='5wy3' size='340' side='right'caption='[[5wy3]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5wy3]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WY3 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5WY3 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5wy3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Chaetomium_thermophilum_var._thermophilum_DSM_1495 Chaetomium thermophilum var. thermophilum DSM 1495]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WY3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5WY3 FirstGlance]. <br>
-
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5wy4|5wy4]]</td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5wy3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wy3 OCA], [http://pdbe.org/5wy3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wy3 RCSB], [http://www.ebi.ac.uk/pdbsum/5wy3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wy3 ProSAT]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5wy3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wy3 OCA], [https://pdbe.org/5wy3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5wy3 RCSB], [https://www.ebi.ac.uk/pdbsum/5wy3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5wy3 ProSAT]</span></td></tr>
</table>
</table>
-
<div style="background-color:#fffaf0;">
+
== Function ==
-
== Publication Abstract from PubMed ==
+
[https://www.uniprot.org/uniprot/G0S5L1_CHATD G0S5L1_CHATD]
-
Eukaryotic small ribosomal subunits are first assembled into 90S pre-ribosomes. The complete 90S is a gigantic complex with a molecular mass of approximately five megadaltons. Here, we report the nearly complete architecture of Saccharomyces cerevisiae 90S determined from three cryo-electron microscopy single particle reconstructions at 4.5 to 8.7 angstrom resolution. The majority of the density maps were modeled and assigned to specific RNA and protein components. The nascent ribosome is assembled into isolated native-like substructures that are stabilized by abundant assembly factors. The 5' external transcribed spacer and U3 snoRNA nucleate a large subcomplex that scaffolds the nascent ribosome. U3 binds four sites of pre-rRNA, including a novel site on helix 27 but not the 3' side of the central pseudoknot, and crucially organizes the 90S structure. The 90S model provides significant insight into the principle of small subunit assembly and the function of assembly factors.
+
-
 
+
-
Molecular architecture of the 90S small subunit pre-ribosome.,Sun Q, Zhu X, Qi J, An W, Lan P, Tan D, Chen R, Wang B, Zheng S, Zhang C, Chen X, Zhang W, Chen J, Dong MQ, Ye K Elife. 2017 Feb 28;6. pii: e22086. doi: 10.7554/eLife.22086. PMID:28244370<ref>PMID:28244370</ref>
+
-
 
+
-
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
+
-
</div>
+
-
<div class="pdbe-citations 5wy3" style="background-color:#fffaf0;"></div>
+
-
== References ==
+
-
<references/>
+
__TOC__
__TOC__
</StructureSection>
</StructureSection>
 +
[[Category: Chaetomium thermophilum var. thermophilum DSM 1495]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Chen, R]]
+
[[Category: Chen R]]
-
[[Category: Ye, K]]
+
[[Category: Ye K]]
-
[[Category: Zhu, X]]
+
[[Category: Zhu X]]
-
[[Category: Components of 90s preribosome]]
+
-
[[Category: Nuclear protein]]
+
-
[[Category: Nucleolar protein]]
+
-
[[Category: Ribosomal protein]]
+

Current revision

Crystal structure of Chaetomium thermophilum Utp10 middle domain

PDB ID 5wy3

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools