Sandbox GGC10

From Proteopedia

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Lysozyme C (1RE2), a human lysosome labelled with two 2’,3’-epoxypropyl beta-glycoside of n-acetyllactosamine
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==Name of your Protein==
<StructureSection load='3VEV' size='340' side='right' caption='Caption for this structure' scene=''>
<StructureSection load='3VEV' size='340' side='right' caption='Caption for this structure' scene=''>
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This is a default text for your page '''Sandbox GGC10'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.
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This is a default text for your page. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.
== Function ==
== Function ==
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This protein has primarily a bacteriolytic function. The lysozymes in tissues and body fluids can be commonly associated with the monocyte-macrophage system and they can also enhance the activity of the immunoagents. Lysozyme C has the capability to perform both hydrolysis and transglycosylation. It also shows a little bit of esterase activity. Lysozyme C can act rapidly on both peptide-substituted and unsubstituted peptidoglycan, but it acts slowly on chitin oligosaccharides. This protein has some catalytic activity too. There is hydrolysis of 1->4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine leaves a residue in a peptidoglycan and between N-acetyl-D-glucosamine has a residue in chitodextrins.
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== Disease ==
== Disease ==
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This protein is involved in the disease called Amyloidosis 8 (AMYL8). This disease is caused by a mutation that affects the gene on the lysozyme C. The description of this disease states that it is a form of a hereditary generalized amyloidosis. It is clinically featured including extensive visceral amyloid deposits, renal amyloidosis resulting in nephrotic syndrome, arterial hypertension, hepatosplenomegaly, cholestasis, and petechial skin rash. This disease is not involved with the nervous system.
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== Relevance ==
== Relevance ==

Revision as of 15:34, 10 February 2021

Name of your Protein

Caption for this structure

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References

  1. ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
  2. ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
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