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5xwe
From Proteopedia
(Difference between revisions)
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<StructureSection load='5xwe' size='340' side='right'caption='[[5xwe]], [[Resolution|resolution]] 1.80Å' scene=''> | <StructureSection load='5xwe' size='340' side='right'caption='[[5xwe]], [[Resolution|resolution]] 1.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5xwe]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[5xwe]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Ophiophagus_hannah Ophiophagus hannah]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XWE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5XWE FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand= | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5xwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xwe OCA], [https://pdbe.org/5xwe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5xwe RCSB], [https://www.ebi.ac.uk/pdbsum/5xwe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5xwe ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/3S11H_OPHHA 3S11H_OPHHA]] Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission.[UniProtKB:P60775] |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 14:41, 2 June 2021
Structure of a three finger toxin from Ophiophagus hannah venom
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