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5xxf

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Current revision (08:17, 22 November 2023) (edit) (undo)
 
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<StructureSection load='5xxf' size='340' side='right'caption='[[5xxf]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
<StructureSection load='5xxf' size='340' side='right'caption='[[5xxf]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5xxf]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XXF OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5XXF FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5xxf]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe] and [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe_972h- Schizosaccharomyces pombe 972h-]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XXF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5XXF FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5xxe|5xxe]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5xxf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xxf OCA], [http://pdbe.org/5xxf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xxf RCSB], [http://www.ebi.ac.uk/pdbsum/5xxf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xxf ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5xxf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xxf OCA], [https://pdbe.org/5xxf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5xxf RCSB], [https://www.ebi.ac.uk/pdbsum/5xxf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5xxf ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/POZ1_SCHPO POZ1_SCHPO]] Telomeric DNA-binding protein that negatively regulates telomerase and telomere length.<ref>PMID:18535244</ref> [[http://www.uniprot.org/uniprot/TPZ1_SCHPO TPZ1_SCHPO]] Telomeric DNA-binding protein that is required to protect the 3'-end telomeric overhang and involved in telomere length regulation. recruits poz1 and ccq1 to telomeres, regulating telomere length negatively and positivels respectively.<ref>PMID:16303567</ref> <ref>PMID:18535244</ref>
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[https://www.uniprot.org/uniprot/POZ1_SCHPO POZ1_SCHPO] Telomeric DNA-binding protein that negatively regulates telomerase and telomere length.<ref>PMID:18535244</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Chen, H]]
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[[Category: Schizosaccharomyces pombe]]
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[[Category: Lei, M]]
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[[Category: Schizosaccharomyces pombe 972h-]]
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[[Category: Wu, J]]
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[[Category: Chen H]]
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[[Category: Xue, J]]
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[[Category: Lei M]]
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[[Category: Dna binding protein]]
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[[Category: Wu J]]
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[[Category: Hub]]
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[[Category: Xue J]]
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[[Category: Sheterin]]
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[[Category: Telomere]]
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Current revision

Crystal structure of Poz1, Tpz1 and Rap1

PDB ID 5xxf

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