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Pyruvate dehydrogenase kinase

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== Structural highlights ==
== Structural highlights ==
<scene name='48/485629/Cv/11'>The active site cleft of PDK4 binds AMPPNP</scene><ref>PMID:21904029</ref>. Water molecules are shown as red spheres. <scene name='48/485629/Cv/12'>Mg coordination site</scene>.
<scene name='48/485629/Cv/11'>The active site cleft of PDK4 binds AMPPNP</scene><ref>PMID:21904029</ref>. Water molecules are shown as red spheres. <scene name='48/485629/Cv/12'>Mg coordination site</scene>.
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</StructureSection>
 
==3D structures of pyruvate dehydrogenase kinase==
==3D structures of pyruvate dehydrogenase kinase==
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**[[2bu7]] - hPDK2 + acetamide derivative<br />
**[[2bu7]] - hPDK2 + acetamide derivative<br />
**[[2bu8]] - hPDK2 + dichloro-acetic acid + ADP<BR />
**[[2bu8]] - hPDK2 + dichloro-acetic acid + ADP<BR />
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**[[4mp2]], [[4mp7]], [[4mpc]], [[4mpe]], [[4mpn]], [[4v25]], [[4v26]], [[5j6a]], [[5j71]], [[5m4k]], [[5m4m]], [[5m4n]], [[5m4p]] – hPDK2 + inhibitor<br />
+
**[[4mp2]], [[4mp7]], [[4mpc]], [[4mpe]], [[4mpn]], [[4v25]], [[4v26]], [[5j6a]], [[5j71]], [[5m4k]], [[5m4m]], [[5m4n]], [[5m4p]], [[6lil]], [[6lio]], [[6lin]], [[6tmz]], [[6tmp]], [[6tmq]], [[6tn0]], [[6tn2]] – hPDK2 + inhibitor<br />
**[[3crk]], [[3crl]] – hPDK2 + pyruvate dehydrogenase E2
**[[3crk]], [[3crl]] – hPDK2 + pyruvate dehydrogenase E2
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== References ==
== References ==
<references/>
<references/>
 +
</StructureSection>
[[Category: Topic Page]]
[[Category: Topic Page]]

Revision as of 07:26, 14 October 2020

Human pyruvate dehydrogenase kinase isozyme 4 dimer complex with AMPPNP and Mg+2 ion (green) (PDB entry 2e0a)

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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