3dax
From Proteopedia
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<StructureSection load='3dax' size='340' side='right'caption='[[3dax]], [[Resolution|resolution]] 2.15Å' scene=''> | <StructureSection load='3dax' size='340' side='right'caption='[[3dax]], [[Resolution|resolution]] 2.15Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3dax]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3dax]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DAX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DAX FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dax FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dax OCA], [https://pdbe.org/3dax PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dax RCSB], [https://www.ebi.ac.uk/pdbsum/3dax PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dax ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/CP7A1_HUMAN CP7A1_HUMAN] Catalyzes a rate-limiting step in cholesterol catabolism and bile acid biosynthesis by introducing a hydrophilic moiety at position 7 of cholesterol. Important for cholesterol homeostasis.<ref>PMID:19965590</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
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[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Arrowsmith | + | [[Category: Arrowsmith CH]] |
| - | [[Category: Bochkarev | + | [[Category: Bochkarev A]] |
| - | [[Category: Bountra | + | [[Category: Bountra C]] |
| - | [[Category: Dombrovski | + | [[Category: Dombrovski L]] |
| - | [[Category: Dong | + | [[Category: Dong A]] |
| - | [[Category: Edwards | + | [[Category: Edwards AM]] |
| - | [[Category: Loppnau | + | [[Category: Loppnau P]] |
| - | [[Category: Park | + | [[Category: Park H]] |
| - | + | [[Category: Strushkevich NV]] | |
| - | [[Category: Strushkevich | + | [[Category: Tempel W]] |
| - | [[Category: Tempel | + | [[Category: Wilkstrom M]] |
| - | [[Category: Wilkstrom | + | |
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Current revision
Crystal structure of human CYP7A1
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bochkarev A | Bountra C | Dombrovski L | Dong A | Edwards AM | Loppnau P | Park H | Strushkevich NV | Tempel W | Wilkstrom M
