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3dax

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Crystal structure of human CYP7A1

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Retrieved from "http://52.214.119.220/wiki/index.php/3dax"

@@ Line 3: / Line 3: @@
 <StructureSection load='3dax' size='340' side='right'caption='[[3dax]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[3dax]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DAX OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3DAX FirstGlance]. <br>
+<table><tr><td colspan='2'>[[3dax]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DAX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DAX FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CYP7A1, CYP7 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cholesterol_7-alpha-monooxygenase Cholesterol 7-alpha-monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.13.17 1.14.13.17] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dax FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dax OCA], [https://pdbe.org/3dax PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dax RCSB], [https://www.ebi.ac.uk/pdbsum/3dax PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dax ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3dax FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dax OCA], [http://pdbe.org/3dax PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3dax RCSB], [http://www.ebi.ac.uk/pdbsum/3dax PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3dax ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/CP7A1_HUMAN CP7A1_HUMAN]] Catalyzes a rate-limiting step in cholesterol catabolism and bile acid biosynthesis by introducing a hydrophilic moiety at position 7 of cholesterol. Important for cholesterol homeostasis.<ref>PMID:19965590</ref>
+[https://www.uniprot.org/uniprot/CP7A1_HUMAN CP7A1_HUMAN] Catalyzes a rate-limiting step in cholesterol catabolism and bile acid biosynthesis by introducing a hydrophilic moiety at position 7 of cholesterol. Important for cholesterol homeostasis.<ref>PMID:19965590</ref>
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
@@ Line 28: / Line 27: @@
 __TOC__
 </StructureSection>
-[[Category: Cholesterol 7-alpha-monooxygenase]]
+[[Category: Homo sapiens]]
-[[Category: Human]]
 [[Category: Large Structures]]
-[[Category: Arrowsmith, C H]]
+[[Category: Arrowsmith CH]]
-[[Category: Bochkarev, A]]
+[[Category: Bochkarev A]]
-[[Category: Bountra, C]]
+[[Category: Bountra C]]
-[[Category: Dombrovski, L]]
+[[Category: Dombrovski L]]
-[[Category: Dong, A]]
+[[Category: Dong A]]
-[[Category: Edwards, A M]]
+[[Category: Edwards AM]]
-[[Category: Loppnau, P]]
+[[Category: Loppnau P]]
-[[Category: Park, H]]
+[[Category: Park H]]
-[[Category: Structural genomic]]
+[[Category: Strushkevich NV]]
-[[Category: Strushkevich, N V]]
+[[Category: Tempel W]]
-[[Category: Tempel, W]]
+[[Category: Wilkstrom M]]
-[[Category: Wilkstrom, M]]
-[[Category: Cholesterol]]
-[[Category: Cholesterol 7-alpha hydroxylase]]
-[[Category: Cholesterol metabolism]]
-[[Category: Cytochrome p450]]
-[[Category: Endoplasmic reticulum]]
-[[Category: Heme]]
-[[Category: Iron]]
-[[Category: Lipid metabolism]]
-[[Category: Membrane]]
-[[Category: Metal-binding]]
-[[Category: Microsome]]
-[[Category: Monooxygenase]]
-[[Category: Nadp]]
-[[Category: Oxidoreductase]]
-[[Category: Polymorphism]]
-[[Category: Sgc]]
-[[Category: Steroid metabolism]]

3dax

From Proteopedia

Current revision

Crystal structure of human CYP7A1

Structural highlights

Function

Evolutionary Conservation

See Also

References

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