1cwl

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[[Image:1cwl.gif|left|200px]]
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{{STRUCTURE_1cwl| PDB=1cwl | SCENE= }}
{{STRUCTURE_1cwl| PDB=1cwl | SCENE= }}
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'''HUMAN CYCLOPHILIN A COMPLEXED WITH 4 4-HYDROXY-MELEU CYCLOSPORIN'''
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===HUMAN CYCLOPHILIN A COMPLEXED WITH 4 4-HYDROXY-MELEU CYCLOSPORIN===
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==Overview==
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Eight new X-ray structures of different cyclophilin A/cyclosporin-derivative complexes are presented. These structures, combined with the existing three published cyclosporin complexes, provide a useful structural database for the analysis of protein-ligand interactions. The effect of small chemical differences on protein-ligand hydrogen-bonding, van der Waals interactions and water structure is presented.
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(as it appears on PubMed at http://www.pubmed.gov), where 9769216 is the PubMed ID number.
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{{ABSTRACT_PUBMED_9769216}}
==About this Structure==
==About this Structure==
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[[Category: Taylor, P.]]
[[Category: Taylor, P.]]
[[Category: Walkinshaw, M D.]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 13:11:21 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 21:38:14 2008''

Revision as of 18:38, 30 June 2008

Image:1cwl.png

Template:STRUCTURE 1cwl

HUMAN CYCLOPHILIN A COMPLEXED WITH 4 4-HYDROXY-MELEU CYCLOSPORIN

Template:ABSTRACT PUBMED 9769216

About this Structure

1CWL is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

X-ray structures and analysis of 11 cyclosporin derivatives complexed with cyclophilin A., Kallen J, Mikol V, Taylor P, Walkinshaw MD, J Mol Biol. 1998 Oct 23;283(2):435-49. PMID:9769216

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