5ziz

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Current revision (10:28, 27 March 2024) (edit) (undo)
 
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<StructureSection load='5ziz' size='340' side='right'caption='[[5ziz]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='5ziz' size='340' side='right'caption='[[5ziz]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5ziz]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZIZ OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5ZIZ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5ziz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Xanthomonas_campestris Xanthomonas campestris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZIZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ZIZ FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5ziz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ziz OCA], [http://pdbe.org/5ziz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ziz RCSB], [http://www.ebi.ac.uk/pdbsum/5ziz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ziz ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ziz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ziz OCA], [https://pdbe.org/5ziz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ziz RCSB], [https://www.ebi.ac.uk/pdbsum/5ziz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ziz ProSAT]</span></td></tr>
</table>
</table>
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<div style="background-color:#fffaf0;">
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== Function ==
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== Publication Abstract from PubMed ==
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[https://www.uniprot.org/uniprot/A0A3E1L4S6_XANCA A0A3E1L4S6_XANCA]
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Bacteria move toward attractants and away from repellants by rotating their flagellum. The bacterial flagellum assembles through the ordered organization of more than 30 different proteins. Among the diverse flagellar proteins, FlgL forms the junction between the hook and the filament in the flagellum together with FlgK and provides a structural base where flagellin, a filament-forming protein, is inserted for the initiation of filament elongation. However, the functional and structural information available for FlgL is highly limited. To provide structural insights into the cross-linkage between the FlgL junction and the flagellin filament, we determined the crystal structures of FlgL from gram-positive Bacillus cereus (bcFlgL) and gram-negative Xanthomonas campestris (xcFlgL). bcFlgL contains one domain (D1), whereas xcFlgL adopts a two-domain structure that consists of the D1 and D2 domains. The constant D1 domain of FlgL adopts a rod structure that is generated by four longitudinal segments. This four-segment structure is recapitulated in filament and junction proteins but not in hook and rod proteins, allowing us to propose a junction-filament assembly mechanism based on a quasi-homotypic interaction. The D2 domain of xcFlgL resembles that of another junction protein, FlgK, suggesting the structural and functional relatedness of FlgL and FlgK.
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Crystal structure of FlgL and its implications for flagellar assembly.,Hong HJ, Kim TH, Song WS, Ko HJ, Lee GS, Kang SG, Kim PH, Yoon SI Sci Rep. 2018 Sep 24;8(1):14307. doi: 10.1038/s41598-018-32460-9. PMID:30250171<ref>PMID:30250171</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 5ziz" style="background-color:#fffaf0;"></div>
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==See Also==
==See Also==
*[[Flagellar protein 3D structures|Flagellar protein 3D structures]]
*[[Flagellar protein 3D structures|Flagellar protein 3D structures]]
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== References ==
 
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<references/>
 
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Hong, H J]]
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[[Category: Xanthomonas campestris]]
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[[Category: Kim, T H]]
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[[Category: Hong HJ]]
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[[Category: Song, W S]]
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[[Category: Kim TH]]
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[[Category: Yoon, S I]]
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[[Category: Song WS]]
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[[Category: Flagellum]]
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[[Category: Yoon SI]]
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[[Category: Junction]]
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[[Category: Structural protein]]
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Current revision

Crystal structure of Xanthomonas campestris FlgL (space group H3)

PDB ID 5ziz

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