6m22
From Proteopedia
(Difference between revisions)
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==KCC3 bound with DIOA== | ==KCC3 bound with DIOA== | ||
| - | <StructureSection load='6m22' size='340' side='right'caption='[[6m22]]' scene=''> | + | <StructureSection load='6m22' size='340' side='right'caption='[[6m22]], [[Resolution|resolution]] 2.70Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6M22 OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[6m22]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6M22 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6M22 FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EZC:2-[[(2~{R})-2-butyl-6,7-bis(chloranyl)-2-cyclopentyl-1-oxidanylidene-3~{H}-inden-5-yl]oxy]ethanoic+acid'>EZC</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> |
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">KCC3 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6m22 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6m22 OCA], [https://pdbe.org/6m22 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6m22 RCSB], [https://www.ebi.ac.uk/pdbsum/6m22 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6m22 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Disease == | ||
| + | [[https://www.uniprot.org/uniprot/S12A6_HUMAN S12A6_HUMAN]] Corpus callosum agenesis-neuronopathy syndrome. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/S12A6_HUMAN S12A6_HUMAN]] Mediates electroneutral potassium-chloride cotransport. May be activated by cell swelling. May contribute to cell volume homeostasis in single cells. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Chen Y]] | + | [[Category: Chen, Y]] |
| - | [[Category: Chi | + | [[Category: Chi, X M]] |
| - | [[Category: Li | + | [[Category: Li, X R]] |
| - | [[Category: Su Q]] | + | [[Category: Su, Q]] |
| - | [[Category: Zhang | + | [[Category: Zhang, Y Y]] |
| - | [[Category: Zhou Q]] | + | [[Category: Zhou, Q]] |
| + | [[Category: Membrane protein]] | ||
Revision as of 10:14, 19 May 2021
KCC3 bound with DIOA
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Categories: Human | Large Structures | Chen, Y | Chi, X M | Li, X R | Su, Q | Zhang, Y Y | Zhou, Q | Membrane protein
