3nr2

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<StructureSection load='3nr2' size='340' side='right'caption='[[3nr2]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
<StructureSection load='3nr2' size='340' side='right'caption='[[3nr2]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3nr2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NR2 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3NR2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3nr2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NR2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NR2 FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3od5|3od5]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3od5|3od5]]</div></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Caspase-6 Caspase-6], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.59 3.4.22.59] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Caspase-6 Caspase-6], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.59 3.4.22.59] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3nr2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nr2 OCA], [http://pdbe.org/3nr2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3nr2 RCSB], [http://www.ebi.ac.uk/pdbsum/3nr2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3nr2 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nr2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nr2 OCA], [https://pdbe.org/3nr2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nr2 RCSB], [https://www.ebi.ac.uk/pdbsum/3nr2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nr2 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CASP6_HUMAN CASP6_HUMAN]] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.
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[[https://www.uniprot.org/uniprot/CASP6_HUMAN CASP6_HUMAN]] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==

Revision as of 05:26, 10 August 2022

Crystal structure of Caspase-6 zymogen

PDB ID 3nr2

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OCA

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