EPSP synthase

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*5-enolpyruvylshikimate 3-phosphate (EPSP) synthase
*5-enolpyruvylshikimate 3-phosphate (EPSP) synthase
 +
**[[7pxy]] – EPSP – ''Arabidopsis thaliana''<br />
**[[1eps]] – EcEPSP – ''Escherichia coli''<br />
**[[1eps]] – EcEPSP – ''Escherichia coli''<br />
**[[1p88]], [[1p89]] - EcEPSP N terminal - NMR<br />
**[[1p88]], [[1p89]] - EcEPSP N terminal - NMR<br />
**[[1rf5]] - SpEPSP – ''Streptococcus pneumoniae''<br />
**[[1rf5]] - SpEPSP – ''Streptococcus pneumoniae''<br />
 +
**[[7m0o]] - EPSP – ''Streptococcus sviceus''<br />
**[[2bjb]], [[2o15]] – MtEPSP – ''Mycobacterium tuberculosis''<br />
**[[2bjb]], [[2o15]] – MtEPSP – ''Mycobacterium tuberculosis''<br />
**[[2gg4]] – AgEPSP – ''Agrobacterium''<br />
**[[2gg4]] – AgEPSP – ''Agrobacterium''<br />
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**[[3ti2]] - VcEPSP N terminal – ''Vibrio cholerae''<br />
**[[3ti2]] - VcEPSP N terminal – ''Vibrio cholerae''<br />
**[[3rmt]] – EPSP – ''Bacillus halodurans''<br />
**[[3rmt]] – EPSP – ''Bacillus halodurans''<br />
 +
**[[5bs5]], [[5buf]] – EPSP – ''Acinetobacter baumannii''<br />
 +
**[[7tm4]] - KpEPSP – ''Klebsiella pneumaniae''<br />
*EPSP synthase binary complex
*EPSP synthase binary complex

Revision as of 08:57, 23 February 2023

Structure of E. coli EPSP synthase complex with shikimate-3-phosphate, the herbicide glyphosate and formic acid (PDB entry 1g6s)

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3D structures of EPSP synthase

Updated on 23-February-2023

References

  1. Priestman MA, Healy ML, Funke T, Becker A, Schonbrunn E. Molecular basis for the glyphosate-insensitivity of the reaction of 5-enolpyruvylshikimate 3-phosphate synthase with shikimate. FEBS Lett. 2005 Oct 24;579(25):5773-80. PMID:16225867 doi:10.1016/j.febslet.2005.09.066
  2. Funke T, Han H, Healy-Fried ML, Fischer M, Schonbrunn E. Molecular basis for the herbicide resistance of Roundup Ready crops. Proc Natl Acad Sci U S A. 2006 Aug 29;103(35):13010-5. Epub 2006 Aug 17. PMID:16916934
  3. Schonbrunn E, Eschenburg S, Shuttleworth WA, Schloss JV, Amrhein N, Evans JN, Kabsch W. Interaction of the herbicide glyphosate with its target enzyme 5-enolpyruvylshikimate 3-phosphate synthase in atomic detail. Proc Natl Acad Sci U S A. 2001 Feb 13;98(4):1376-80. PMID:11171958 doi:http://dx.doi.org/10.1073/pnas.98.4.1376

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