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6caz

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Current revision (15:00, 4 October 2023) (edit) (undo)
 
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<StructureSection load='6caz' size='340' side='right'caption='[[6caz]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
<StructureSection load='6caz' size='340' side='right'caption='[[6caz]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6caz]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CAZ OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6CAZ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6caz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Legionella_pneumophila_subsp._pneumophila_str._Philadelphia_1 Legionella pneumophila subsp. pneumophila str. Philadelphia 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CAZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6CAZ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptide_deformylase Peptide deformylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.88 3.5.1.88] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6caz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6caz OCA], [http://pdbe.org/6caz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6caz RCSB], [http://www.ebi.ac.uk/pdbsum/6caz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6caz ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6caz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6caz OCA], [https://pdbe.org/6caz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6caz RCSB], [https://www.ebi.ac.uk/pdbsum/6caz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6caz ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/Q5ZSC4_LEGPH Q5ZSC4_LEGPH]] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.[HAMAP-Rule:MF_00163]
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[https://www.uniprot.org/uniprot/Q5ZSC4_LEGPH Q5ZSC4_LEGPH] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.[HAMAP-Rule:MF_00163]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Peptide deformylase]]
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[[Category: Legionella pneumophila subsp. pneumophila str. Philadelphia 1]]
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[[Category: Structural genomic]]
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[[Category: Gram-negative bacteria]]
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[[Category: Hydrolase]]
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[[Category: Legionellosis]]
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[[Category: Legionnaires' disease]]
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[[Category: Metalloenzyme]]
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[[Category: Niaid]]
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[[Category: Ssgcid]]
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Current revision

Crystal structure of a peptide deformylase from Legionella pneumophila

PDB ID 6caz

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