6d47

<table><tr><td colspan='2'>[[6d47]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6D47 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6D47 FirstGlance]. <br>

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6d47 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6d47 OCA], [http://pdbe.org/6d47 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6d47 RCSB], [http://www.ebi.ac.uk/pdbsum/6d47 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6d47 ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/B2HI47_MYCMM B2HI47_MYCMM]] Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.[PIRNR:PIRNR000804]

[[Category: Structural genomic]]

[[Category: Tuberculosis]]