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7cvx
From Proteopedia
(Difference between revisions)
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==Crystal structure of Catechol o-methyl transferase (COMT) from Niastella koreensis== | ==Crystal structure of Catechol o-methyl transferase (COMT) from Niastella koreensis== | ||
| - | <StructureSection load='7cvx' size='340' side='right'caption='[[7cvx]]' scene=''> | + | <StructureSection load='7cvx' size='340' side='right'caption='[[7cvx]], [[Resolution|resolution]] 1.70Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CVX OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[7cvx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Niastella_koreensis_GR20-10 Niastella koreensis GR20-10]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CVX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7CVX FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DHB:3,4-DIHYDROXYBENZOIC+ACID'>DHB</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7cvx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7cvx OCA], [https://pdbe.org/7cvx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7cvx RCSB], [https://www.ebi.ac.uk/pdbsum/7cvx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7cvx ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CAMT_NIAKG CAMT_NIAKG] Catechol O-methyltransferase that can use various catechol-like compounds (PubMed:33596655). Can produce vanillic acid (meta-form) and iso-vanillic acid (para-form) from protocatechuic acid (PCA) (PubMed:33596655). Does not have a regiospecificity, and produces the meta- and para-forms of the products in equal proportion (PubMed:33596655).<ref>PMID:33596655</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| + | [[Category: Niastella koreensis GR20-10]] | ||
[[Category: Kim B]] | [[Category: Kim B]] | ||
[[Category: Kim K-J]] | [[Category: Kim K-J]] | ||
[[Category: Lee SH]] | [[Category: Lee SH]] | ||
Current revision
Crystal structure of Catechol o-methyl transferase (COMT) from Niastella koreensis
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