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7k3w
From Proteopedia
(Difference between revisions)
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==Apoferritin structure at 1.36 angstrom resolution determined from a 300 kV Titan Krios G3i electron microscope with Falcon4 detector== | ==Apoferritin structure at 1.36 angstrom resolution determined from a 300 kV Titan Krios G3i electron microscope with Falcon4 detector== | ||
| - | <StructureSection load='7k3w' size='340' side='right'caption='[[7k3w]]' scene=''> | + | <StructureSection load='7k3w' size='340' side='right'caption='[[7k3w]], [[Resolution|resolution]] 1.36Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7K3W OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=7K3W FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7k3w]] is a 24 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7K3W OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=7K3W FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=7k3w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7k3w OCA], [http://pdbe.org/7k3w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7k3w RCSB], [http://www.ebi.ac.uk/pdbsum/7k3w PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=7k3w ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FTH1, FTH, FTHL6, OK/SW-cl.84, PIG15 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ferroxidase Ferroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.16.3.1 1.16.3.1] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=7k3w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7k3w OCA], [http://pdbe.org/7k3w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7k3w RCSB], [http://www.ebi.ac.uk/pdbsum/7k3w PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=7k3w ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/FRIH_HUMAN FRIH_HUMAN]] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity). | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Ferroxidase]] | ||
| + | [[Category: Human]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Chiu W]] | + | [[Category: Chiu, W]] |
| - | [[Category: Li S]] | + | [[Category: Li, S]] |
| - | [[Category: Pintilie G]] | + | [[Category: Pintilie, G]] |
| - | [[Category: Schmid M]] | + | [[Category: Schmid, M]] |
| - | [[Category: Zhang K]] | + | [[Category: Zhang, K]] |
| + | [[Category: Apoferritin]] | ||
| + | [[Category: Atomic resolution]] | ||
| + | [[Category: Cryo-em]] | ||
| + | [[Category: Falcon4 detector]] | ||
| + | [[Category: Oxidoreductase]] | ||
Revision as of 13:01, 16 December 2020
Apoferritin structure at 1.36 angstrom resolution determined from a 300 kV Titan Krios G3i electron microscope with Falcon4 detector
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Categories: Ferroxidase | Human | Large Structures | Chiu, W | Li, S | Pintilie, G | Schmid, M | Zhang, K | Apoferritin | Atomic resolution | Cryo-em | Falcon4 detector | Oxidoreductase
