7kem
From Proteopedia
(Difference between revisions)
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==Crystallographic structure of L,D-transpeptidase 2 from Mycobacterium tuberculosis== | ==Crystallographic structure of L,D-transpeptidase 2 from Mycobacterium tuberculosis== | ||
| - | <StructureSection load='7kem' size='340' side='right'caption='[[7kem]]' scene=''> | + | <StructureSection load='7kem' size='340' side='right'caption='[[7kem]], [[Resolution|resolution]] 1.77Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KEM OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[7kem]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KEM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KEM FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.77Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0JC:DI-MU-IODOBIS(ETHYLENEDIAMINE)DIPLATINUM(II)'>0JC</scene>, <scene name='pdbligand=6CL:6-CARBOXYLYSINE'>6CL</scene>, <scene name='pdbligand=DGL:D-GLUTAMIC+ACID'>DGL</scene>, <scene name='pdbligand=PT:PLATINUM+(II)+ION'>PT</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kem FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kem OCA], [https://pdbe.org/7kem PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kem RCSB], [https://www.ebi.ac.uk/pdbsum/7kem PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kem ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/LDT2_MYCTU LDT2_MYCTU] Generates 3->3 cross-links in peptidoglycan, catalyzing the cleavage of the mDap(3)-D-Ala(4) bond of a tetrapeptide donor stem and the formation of a bond between the carbonyl of mDap(3) of the donor stem and the side chain of mDap(3) of the acceptor stem. Is specific for donor substrates containing a stem tetrapeptide since it cannot use pentapeptide stems.<ref>PMID:24041897</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| + | [[Category: Mycobacterium tuberculosis H37Rv]] | ||
[[Category: Dias MVB]] | [[Category: Dias MVB]] | ||
[[Category: Libreros GA]] | [[Category: Libreros GA]] | ||
Current revision
Crystallographic structure of L,D-transpeptidase 2 from Mycobacterium tuberculosis
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