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1hbx

From Proteopedia

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Current revision (12:23, 13 December 2023) (edit) (undo)
 
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<StructureSection load='1hbx' size='340' side='right'caption='[[1hbx]], [[Resolution|resolution]] 3.15&Aring;' scene=''>
<StructureSection load='1hbx' size='340' side='right'caption='[[1hbx]], [[Resolution|resolution]] 3.15&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1hbx]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HBX OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1HBX FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1hbx]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HBX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HBX FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1bc7|1bc7]], [[1bc8|1bc8]], [[1srs|1srs]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.15&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SRF (132-223) ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), SAP-1 (1-156) ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hbx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hbx OCA], [https://pdbe.org/1hbx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hbx RCSB], [https://www.ebi.ac.uk/pdbsum/1hbx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hbx ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1hbx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hbx OCA], [http://pdbe.org/1hbx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1hbx RCSB], [http://www.ebi.ac.uk/pdbsum/1hbx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1hbx ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/SRF_HUMAN SRF_HUMAN]] SRF is a transcription factor that binds to the serum response element (SRE), a short sequence of dyad symmetry located 300 bp to the 5' of the site of transcription initiation of some genes (such as FOS). Required for cardiac differentiation and maturation.
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[https://www.uniprot.org/uniprot/SRF_HUMAN SRF_HUMAN] SRF is a transcription factor that binds to the serum response element (SRE), a short sequence of dyad symmetry located 300 bp to the 5' of the site of transcription initiation of some genes (such as FOS). Required for cardiac differentiation and maturation.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Hassler, M]]
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[[Category: Hassler M]]
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[[Category: Richmond, T J]]
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[[Category: Richmond TJ]]
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[[Category: Gene regulation]]
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[[Category: Serum response factor]]
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[[Category: Ternary complex factor]]
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[[Category: Transcription complex]]
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Current revision

Ternary Complex of SAP-1 and SRF with specific SRE DNA

PDB ID 1hbx

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OCA

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