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Mycobacterium Tuberculosis Transpeptidase Domain
From Proteopedia
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== Structural highlights == | == Structural highlights == | ||
| - | Penicillin V binds to the transpeptidase domain of this protein. <scene name='86/867346/Fig_4a/ | + | Penicillin V binds to the transpeptidase domain of this protein. <scene name='86/867346/Fig_4a/6'>In this view</scene>, penicillin V is shown as ball and stick, with the carbon atoms in red. |
</StructureSection> | </StructureSection> | ||
Revision as of 14:40, 17 December 2020
Mtb Transpeptidase Domain in Complex with Penicillin
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References
Filippova, E. V., Kieser, K. J., Luan, C. H., Wawrzak, Z., Kiryukhina, O., Rubin, E. J., & Anderson, W. F. (2016). Crystal structures of the transpeptidase domain of the Mycobacterium tuberculosis penicillin‐binding protein PonA1 reveal potential mechanisms of antibiotic resistance. The FEBS journal, 283(12), 2206-2218.
Maria-Magdalena Patru, Martin S. Pavelka, Jr. A Role for the Class A Penicillin-Binding Protein PonA2 in the Survival of Mycobacterium smegmatis under Conditions of Nonreplication, J Bacteriol. 2010 Jun; 192(12): 3043–3054. Published online 2010 Apr 16. doi: 10.1128/JB.00025-10
