1d59

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{{STRUCTURE_1d59| PDB=1d59 | SCENE= }}
{{STRUCTURE_1d59| PDB=1d59 | SCENE= }}
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'''CRYSTAL STRUCTURE OF 4-STRANDED OXYTRICHA TELOMERIC DNA'''
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===CRYSTAL STRUCTURE OF 4-STRANDED OXYTRICHA TELOMERIC DNA===
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==Overview==
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The sequence d(GGGGTTTTGGGG) from the 3' overhang of the Oxytricha telomere has been crystallized and its three-dimensional structure solved to 2.5 A resolution. The oligonucleotide forms hairpins, two of which join to make a four-stranded helical structure with the loops containing four thymine residues at either end. The guanine residues are held together by cyclic hydrogen bonding and an ion is located in the centre. The four guanine residues in each segment have a glycosyl conformation that alternates between anti and syn. There are two four-stranded molecules in the asymmetric unit showing that the structure has some intrinsic flexibility.
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(as it appears on PubMed at http://www.pubmed.gov), where 1545863 is the PubMed ID number.
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{{ABSTRACT_PUBMED_1545863}}
==About this Structure==
==About this Structure==
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[[Category: Tetraplex]]
[[Category: Tetraplex]]
[[Category: U-dna]]
[[Category: U-dna]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 13:27:55 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 22:26:30 2008''

Revision as of 19:26, 30 June 2008

Image:1d59.png

Template:STRUCTURE 1d59

CRYSTAL STRUCTURE OF 4-STRANDED OXYTRICHA TELOMERIC DNA

Template:ABSTRACT PUBMED 1545863

About this Structure

Full crystallographic information is available from OCA.

Reference

Crystal structure of four-stranded Oxytricha telomeric DNA., Kang C, Zhang X, Ratliff R, Moyzis R, Rich A, Nature. 1992 Mar 12;356(6365):126-31. PMID:1545863

Page seeded by OCA on Mon Jun 30 22:26:30 2008

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