7k3v

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Current revision (14:55, 6 March 2024) (edit) (undo)
 
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<StructureSection load='7k3v' size='340' side='right'caption='[[7k3v]], [[Resolution|resolution]] 1.34&Aring;' scene=''>
<StructureSection load='7k3v' size='340' side='right'caption='[[7k3v]], [[Resolution|resolution]] 1.34&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[7k3v]] is a 24 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7K3V OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=7K3V FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7k3v]] is a 24 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7K3V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7K3V FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 1.34&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FTH1, FTH, FTHL6, OK/SW-cl.84, PIG15 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ferroxidase Ferroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.16.3.1 1.16.3.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7k3v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7k3v OCA], [https://pdbe.org/7k3v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7k3v RCSB], [https://www.ebi.ac.uk/pdbsum/7k3v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7k3v ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=7k3v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7k3v OCA], [http://pdbe.org/7k3v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7k3v RCSB], [http://www.ebi.ac.uk/pdbsum/7k3v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=7k3v ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/FRIH_HUMAN FRIH_HUMAN]] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity).
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[https://www.uniprot.org/uniprot/FRIH_HUMAN FRIH_HUMAN] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity).
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==See Also==
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*[[Ferritin 3D structures|Ferritin 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Ferroxidase]]
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[[Category: Homo sapiens]]
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[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Chiu, W]]
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[[Category: Chiu W]]
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[[Category: Li, S]]
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[[Category: Li S]]
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[[Category: Pintilie, G]]
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[[Category: Pintilie G]]
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[[Category: Schmid, M]]
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[[Category: Schmid M]]
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[[Category: Zhang, K]]
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[[Category: Zhang K]]
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[[Category: Apoferritin]]
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[[Category: Atomic resolution]]
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[[Category: Cryo-em]]
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[[Category: K3 detector]]
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[[Category: Oxidoreductase]]
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Current revision

Apoferritin structure at 1.34 angstrom resolution determined from a 300 kV Titan Krios G3i electron microscope with K3 detector

PDB ID 7k3v

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