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| | <StructureSection load='1jcf' size='340' side='right'caption='[[1jcf]], [[Resolution|resolution]] 2.10Å' scene=''> | | <StructureSection load='1jcf' size='340' side='right'caption='[[1jcf]], [[Resolution|resolution]] 2.10Å' scene=''> |
| | == Structural highlights == | | == Structural highlights == |
| - | <table><tr><td colspan='2'>[[1jcf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43589 Atcc 43589]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JCF OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1JCF FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[1jcf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JCF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JCF FirstGlance]. <br> |
| - | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1jce|1jce]], [[1jcg|1jcg]]</div></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TM0588 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2336 ATCC 43589])</td></tr>
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jcf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jcf OCA], [https://pdbe.org/1jcf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jcf RCSB], [https://www.ebi.ac.uk/pdbsum/1jcf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jcf ProSAT]</span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1jcf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jcf OCA], [http://pdbe.org/1jcf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1jcf RCSB], [http://www.ebi.ac.uk/pdbsum/1jcf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1jcf ProSAT]</span></td></tr> | + | |
| | </table> | | </table> |
| | + | == Function == |
| | + | [https://www.uniprot.org/uniprot/Q9WZ57_THEMA Q9WZ57_THEMA] |
| | == Evolutionary Conservation == | | == Evolutionary Conservation == |
| | [[Image:Consurf_key_small.gif|200px|right]] | | [[Image:Consurf_key_small.gif|200px|right]] |
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| | __TOC__ | | __TOC__ |
| | </StructureSection> | | </StructureSection> |
| - | [[Category: Atcc 43589]] | |
| | [[Category: Large Structures]] | | [[Category: Large Structures]] |
| - | [[Category: Amos, L A]] | + | [[Category: Thermotoga maritima]] |
| - | [[Category: Ent, F van den]] | + | [[Category: Amos LA]] |
| - | [[Category: Lowe, J]] | + | [[Category: Lowe J]] |
| - | [[Category: Actin]] | + | [[Category: Van den Ent F]] |
| - | [[Category: Ftsz]]
| + | |
| - | [[Category: Hsp-70]]
| + | |
| - | [[Category: Mbl]]
| + | |
| - | [[Category: Mreb]]
| + | |
| - | [[Category: Rod-shape determining]]
| + | |
| - | [[Category: Structural protein]]
| + | |
| Structural highlights
Function
Q9WZ57_THEMA
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
Publication Abstract from PubMed
It was thought until recently that bacteria lack the actin or tubulin filament networks that organize eukaryotic cytoplasm. However, we show here that the bacterial MreB protein assembles into filaments with a subunit repeat similar to that of F-actin-the physiological polymer of eukaryotic actin. By elucidating the MreB crystal structure we demonstrate that MreB and actin are very similar in three dimensions. Moreover, the crystals contain protofilaments, allowing visualization of actin-like strands at atomic resolution. The structure of the MreB protofilament is in remarkably good agreement with the model for F-actin, showing that the proteins assemble in identical orientations. The actin-like properties of MreB explain the finding that MreB forms large fibrous spirals under the cell membrane of rod-shaped cells, where they are involved in cell-shape determination. Thus, prokaryotes are now known to possess homologues both of tubulin, namely FtsZ, and of actin.
Prokaryotic origin of the actin cytoskeleton.,van den Ent F, Amos LA, Lowe J Nature. 2001 Sep 6;413(6851):39-44. PMID:11544518[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
- ↑ van den Ent F, Amos LA, Lowe J. Prokaryotic origin of the actin cytoskeleton. Nature. 2001 Sep 6;413(6851):39-44. PMID:11544518 doi:http://dx.doi.org/10.1038/35092500
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