Thymidylate synthase 3D structures

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Line 21: Line 21:
**[[3v8h]] – TS – ''Burkholderia thailandensis''<br />
**[[3v8h]] – TS – ''Burkholderia thailandensis''<br />
**[[4h0r]] - CgTS – ''Corynebacterium glutamicum''<br />
**[[4h0r]] - CgTS – ''Corynebacterium glutamicum''<br />
 +
**[[7ta9]] – TS – ''Acinetobacter baumannii''<br />
**[[4xse]] - VvTS – Varicella-zoster virus<br />
**[[4xse]] - VvTS – Varicella-zoster virus<br />
**[[6auj]] - TS – ''Elizabethkingia anophelis''<br />
**[[6auj]] - TS – ''Elizabethkingia anophelis''<br />
**[[7cc8]] - wssvTS – white spot syndrome virus<br />
**[[7cc8]] - wssvTS – white spot syndrome virus<br />
 +
**[[5h38]] – hhvORF70 – human herpesvirus 8<br />
*Thymidylate synthase binary complex with UMP
*Thymidylate synthase binary complex with UMP
Line 47: Line 49:
**[[4foa]] - MtTS + fluoro-UMP – ''Mycobacterium tuberculosis''<br />
**[[4foa]] - MtTS + fluoro-UMP – ''Mycobacterium tuberculosis''<br />
**[[4h0u]] – CgTS + UMP<br />
**[[4h0u]] – CgTS + UMP<br />
 +
**[[7dp6]] – BmaTS (mutant) + UMP – ''Brugia malayi''<br />
**[[4xsc]] - VvTS + d-Uridine derivative <br />
**[[4xsc]] - VvTS + d-Uridine derivative <br />
**[[4xsd]] - VvTS + dUMP<br />
**[[4xsd]] - VvTS + dUMP<br />
 +
**[[5h39]] – hhvORF70 + UMP<br />
*Thymidylate synthase binary complex without UMP
*Thymidylate synthase binary complex without UMP
Line 100: Line 104:
**[[6cdz]] - EcTS (mutant) + deoxyuridine + UMP<br />
**[[6cdz]] - EcTS (mutant) + deoxyuridine + UMP<br />
**[[2kce]], [[1axw]] - EcTS + drug + UMP<BR />
**[[2kce]], [[1axw]] - EcTS + drug + UMP<BR />
 +
**[[7jxf]] - EcTS + bi-substrate + UMP derivative<BR />
 +
**[[7jx1]] - EcTS + bi-substrate + TMP <BR />
**[[1ddu]], [[1tdu]] - EcTS + deoxyuridine derivative + inhibitor<br />
**[[1ddu]], [[1tdu]] - EcTS + deoxyuridine derivative + inhibitor<br />
**[[6cdz]] - EcTS + deoxyuridine + UMP<br />
**[[6cdz]] - EcTS + deoxyuridine + UMP<br />
Line 112: Line 118:
**[[4fox]], [[4fqs]] - MtTS + inhibitor + fluoro-UMP <br />
**[[4fox]], [[4fqs]] - MtTS + inhibitor + fluoro-UMP <br />
**[[6qxs]] - EfTS + fluoro-dUMP + folate derivative<br />
**[[6qxs]] - EfTS + fluoro-dUMP + folate derivative<br />
-
**[[7cca]] - wssvTS + UMP + methotrexate<br />
+
**[[7cca]] - wssvTS + UMP + drug<br />
 +
**[[5h3a]] – hhvORF70 + UMP + drug<br />
 +
**[[7dp4]], [[7dp5]] – BmaTS + UMP + drug <br />
*Thymidylate synthase ternary complex without UMP
*Thymidylate synthase ternary complex without UMP
Line 152: Line 160:
**[[5ioq]], [[5ior]] – TmTS + FAD + d-Uridine derivative<br />
**[[5ioq]], [[5ior]] – TmTS + FAD + d-Uridine derivative<br />
**[[5ios]], [[2iot]] – TmTS (mutant) + FAD + dUMP<br />
**[[5ios]], [[2iot]] – TmTS (mutant) + FAD + dUMP<br />
 +
**[[7ndw]], [[7ndz]] – TmTS + FAD derivative + pteridine derivative<br />
**[[3ge9]] - CgTS<br />
**[[3ge9]] - CgTS<br />
**[[3fnn]] - CgTS + FAD <br />
**[[3fnn]] - CgTS + FAD <br />

Revision as of 10:16, 24 April 2022

3D structures of thymidylate synthase

Updated on 24-April-2022 - For a general description of the protein see Thymidylate synthase

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman

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