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1m62

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<StructureSection load='1m62' size='340' side='right'caption='[[1m62]], [[NMR_Ensembles_of_Models | 25 NMR models]]' scene=''>
<StructureSection load='1m62' size='340' side='right'caption='[[1m62]], [[NMR_Ensembles_of_Models | 25 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1m62]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M62 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1M62 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1m62]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M62 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1M62 FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1i6z|1i6z]], [[1hx1|1hx1]]</div></td></tr>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1i6z|1i6z]], [[1hx1|1hx1]]</div></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BAG4/SODD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BAG4/SODD ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1m62 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m62 OCA], [http://pdbe.org/1m62 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1m62 RCSB], [http://www.ebi.ac.uk/pdbsum/1m62 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1m62 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1m62 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m62 OCA], [https://pdbe.org/1m62 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1m62 RCSB], [https://www.ebi.ac.uk/pdbsum/1m62 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1m62 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/BAG4_HUMAN BAG4_HUMAN]] Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release (By similarity). Prevents constitutive TNFRSF1A signaling.
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[[https://www.uniprot.org/uniprot/BAG4_HUMAN BAG4_HUMAN]] Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release (By similarity). Prevents constitutive TNFRSF1A signaling.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 08:16, 23 February 2022

Solution structure of the BAG domain from BAG4/SODD

PDB ID 1m62

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