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Function of your Protein

are cell wall proteins responsible for for the binding of a bacteria or fungi to its host. My epithelial adhesin is part of the Candida glabrata, Candidiasis are any type of fungal infections resulting from Yeast (candida). Their N-terminal domains are endowed with a calcium-dependent lectin activity. This feature allows the yeast cells to adhere to host cells by establishing multiple interactions with the glycans expressed on their cell membrane. My Protein binds to . Once the fungi binds to its host it can then release enzymes through its hyphae that help it absorb nutrients from the host.

Biological relevance and broader implications

Epithelial Adhesins are important for fungi because they help the organism bind to the host so they can live, gain nurtrients and maintain its steady state. Candida Glabrata which house these epithelial adhesins are the 2nd major cause of clinical candidias, It is most prevelant in vaginal infections but can even cause systemic infections by entrance of the fungal cells in the bloodstream (Candidemia), especially prevalent in immunocompromised patients. it is important to study protiens like epithelial adhesins so we can better understand how fungi and other organisms infect the body, ny undertanding the role of these protiens we can begin to work on combat methods and long term immunity.

Important amino acids

Structural highlights

My protein is a epithelial adhesin protein binded to a Galactose beta 1-3 N-acetyl-D-Glucosamine, it contains 3 to 5 small alpha helices and a core of anti parralel beta sheets. all of the catalytic amino acids bind to the ligand by hydrogen bonds with the ligand itself or metal interaction with Ca+ its also contains a disulfide bond binding two loops together that are crucial in ligand affinity.

Other important features

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