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7a0l

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Current revision (07:43, 1 May 2024) (edit) (undo)
 
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==Joint neutron/X-ray room temperature structure of perdeuterated Aspergillus flavus urate oxidase in complex with the 8-azaxanthine inhibitor and catalytic water bound in the peroxo hole==
==Joint neutron/X-ray room temperature structure of perdeuterated Aspergillus flavus urate oxidase in complex with the 8-azaxanthine inhibitor and catalytic water bound in the peroxo hole==
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<StructureSection load='7a0l' size='340' side='right'caption='[[7a0l]]' scene=''>
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<StructureSection load='7a0l' size='340' side='right'caption='[[7a0l]], [[Resolution|resolution]] 1.33&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7A0L OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=7A0L FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7a0l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aspergillus_flavus Aspergillus flavus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7A0L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7A0L FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=7a0l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7a0l OCA], [http://pdbe.org/7a0l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7a0l RCSB], [http://www.ebi.ac.uk/pdbsum/7a0l PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=7a0l ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Hybrid , Neutron Diffraction , X-ray diffraction, [[Resolution|Resolution]] 1.33&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AZA:8-AZAXANTHINE'>AZA</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7a0l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7a0l OCA], [https://pdbe.org/7a0l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7a0l RCSB], [https://www.ebi.ac.uk/pdbsum/7a0l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7a0l ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/URIC_ASPFL URIC_ASPFL] Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
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==See Also==
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*[[Urate oxidase 3D structures|Urate oxidase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Aspergillus flavus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Blakeley MP]]
[[Category: Blakeley MP]]

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Joint neutron/X-ray room temperature structure of perdeuterated Aspergillus flavus urate oxidase in complex with the 8-azaxanthine inhibitor and catalytic water bound in the peroxo hole

PDB ID 7a0l

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