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1otc

From Proteopedia

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Current revision (23:46, 27 December 2023) (edit) (undo)
 
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<StructureSection load='1otc' size='340' side='right'caption='[[1otc]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='1otc' size='340' side='right'caption='[[1otc]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1otc]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Ciliate Ciliate]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OTC OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1OTC FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1otc]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Sterkiella_nova Sterkiella nova]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OTC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OTC FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MAC-56A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=200597 Ciliate]), MAC-41A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=200597 Ciliate])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1otc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1otc OCA], [http://pdbe.org/1otc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1otc RCSB], [http://www.ebi.ac.uk/pdbsum/1otc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1otc ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1otc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1otc OCA], [https://pdbe.org/1otc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1otc RCSB], [https://www.ebi.ac.uk/pdbsum/1otc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1otc ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/TEBB_OXYNO TEBB_OXYNO]] May function as protective capping of the single-stranded telomeric overhang. May also participate in telomere length regulation during DNA replication. Binds specifically to the T4G4-containing extension on the 3'strand and protects this region of the telomere from nuclease digestion and chemical modification. [[http://www.uniprot.org/uniprot/TEBA_OXYNO TEBA_OXYNO]] May function as protective capping of the single-stranded telomeric overhang. May also participate in telomere length regulation during DNA replication. Binds specifically to the T4G4-containing extension on the 3'strand and protects this region of the telomere from nuclease digestion and chemical modification.
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[https://www.uniprot.org/uniprot/TEBA_STENO TEBA_STENO] May function as protective capping of the single-stranded telomeric overhang. May also participate in telomere length regulation during DNA replication. Binds specifically to the T4G4-containing extension on the 3'strand and protects this region of the telomere from nuclease digestion and chemical modification.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</div>
</div>
<div class="pdbe-citations 1otc" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1otc" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[End-binding protein|End-binding protein]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Ciliate]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Bevilacqua, J M]]
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[[Category: Sterkiella nova]]
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[[Category: Horvath, M P]]
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[[Category: Bevilacqua JM]]
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[[Category: Ruggles, J A]]
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[[Category: Horvath MP]]
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[[Category: Schultz, S C]]
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[[Category: Ruggles JA]]
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[[Category: Schweiker, V L]]
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[[Category: Schultz SC]]
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[[Category: Ob fold]]
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[[Category: Schweiker VL]]
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[[Category: Oligonucleotide and oligosaccharide binding fold]]
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[[Category: Protein dna interaction]]
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[[Category: Protein protein interaction]]
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[[Category: Protein-dna complex]]
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[[Category: Single strand dna binding protein]]
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[[Category: Telomere]]
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Current revision

THE O. NOVA TELOMERE END BINDING PROTEIN COMPLEXED WITH SINGLE STRAND DNA

PDB ID 1otc

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OCA

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