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6tl5
From Proteopedia
(Difference between revisions)
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==Three dimensional structure of human carbonic anhydrase IX in complex with sulfonamide== | ==Three dimensional structure of human carbonic anhydrase IX in complex with sulfonamide== | ||
| - | <StructureSection load='6tl5' size='340' side='right'caption='[[6tl5]]' scene=''> | + | <StructureSection load='6tl5' size='340' side='right'caption='[[6tl5]], [[Resolution|resolution]] 2.21Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TL5 OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[6tl5]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TL5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6TL5 FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.21Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MKQ:3,5-diphenylbenzenesulfonamide'>MKQ</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6tl5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tl5 OCA], [https://pdbe.org/6tl5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6tl5 RCSB], [https://www.ebi.ac.uk/pdbsum/6tl5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6tl5 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CAH9_HUMAN CAH9_HUMAN] Reversible hydration of carbon dioxide. Participates in pH regulation. May be involved in the control of cell proliferation and transformation. Appears to be a novel specific biomarker for a cervical neoplasia.<ref>PMID:18703501</ref> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Carbonic anhydrase 3D structures|Carbonic anhydrase 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Leitans J]] | [[Category: Leitans J]] | ||
[[Category: Tars K]] | [[Category: Tars K]] | ||
Current revision
Three dimensional structure of human carbonic anhydrase IX in complex with sulfonamide
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