1r1d

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<StructureSection load='1r1d' size='340' side='right'caption='[[1r1d]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='1r1d' size='340' side='right'caption='[[1r1d]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1r1d]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_12980 Atcc 12980]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R1D OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1R1D FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1r1d]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R1D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1R1D FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">EST ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1422 ATCC 12980])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1r1d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r1d OCA], [https://pdbe.org/1r1d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1r1d RCSB], [https://www.ebi.ac.uk/pdbsum/1r1d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1r1d ProSAT], [https://www.topsan.org/Proteins/MCSG/1r1d TOPSAN]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carboxylesterase Carboxylesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.1 3.1.1.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1r1d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r1d OCA], [http://pdbe.org/1r1d PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1r1d RCSB], [http://www.ebi.ac.uk/pdbsum/1r1d PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1r1d ProSAT], [http://www.topsan.org/Proteins/MCSG/1r1d TOPSAN]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/EST_GEOSE EST_GEOSE]] Involved in the detoxification of xenobiotics. Shows maximal activity with C6 substrates, with gradually decreasing activity from C8 to C12 substrates. No activity for higher chain length substrates acids rather than long-chain ones.
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[https://www.uniprot.org/uniprot/EST_GEOSE EST_GEOSE] Involved in the detoxification of xenobiotics. Shows maximal activity with C6 substrates, with gradually decreasing activity from C8 to C12 substrates. No activity for higher chain length substrates acids rather than long-chain ones.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 12980]]
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[[Category: Geobacillus stearothermophilus]]
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[[Category: Carboxylesterase]]
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[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Collart, F]]
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[[Category: Collart F]]
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[[Category: Cuff, M E]]
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[[Category: Cuff ME]]
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[[Category: Joachimiak, A]]
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[[Category: Joachimiak A]]
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[[Category: Structural genomic]]
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[[Category: Zhou M]]
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[[Category: Zhou, M]]
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[[Category: Bacillus stearothermophilus]]
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[[Category: Hydrolase]]
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[[Category: Mcsg]]
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[[Category: PSI, Protein structure initiative]]
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Revision as of 06:08, 17 April 2024

Structure of a Carboxylesterase from Bacillus stearothermophilus

PDB ID 1r1d

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