1r9g

<table><tr><td colspan='2'>[[1r9g]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"vibrio_subtilis"_ehrenberg_1835 "vibrio subtilis" ehrenberg 1835]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R9G OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1R9G FirstGlance]. <br>

</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>

<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">YAAE, BSU00120 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 "Vibrio subtilis" Ehrenberg 1835])</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1r9g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r9g OCA], [http://pdbe.org/1r9g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1r9g RCSB], [http://www.ebi.ac.uk/pdbsum/1r9g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1r9g ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/PDXT_BACSU PDXT_BACSU]] Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS.

<div style="background-color:#fffaf0;">

== Publication Abstract from PubMed ==

The structure of YaaE from Bacillus subtilis was determined at 2.5-A resolution. YaaE is a member of the triad glutamine aminotransferase family and functions in a recently identified alternate pathway for the biosynthesis of vitamin B(6). Proposed active residues include conserved Cys-79, His-170, and Glu-172. YaaE shows similarity to HisH, a glutaminase involved in histidine biosynthesis. YaaD associates with YaaE. A homology model of this protein was constructed. YaaD is predicted to be a (beta/alpha)(8) barrel on the basis of sequence comparisons. The predicted active site includes highly conserved residues 211-216 and 233-235. Finally, a homology model of a putative YaaD-YaaE complex was prepared using the structure of HisH-F as a model. This model predicts that the ammonia molecule generated by YaaE is channeled through the center of the YaaD barrel to the putative YaaD active site.

Three-dimensional structure of YaaE from Bacillus subtilis, a glutaminase implicated in pyridoxal-5'-phosphate biosynthesis.,Bauer JA, Bennett EM, Begley TP, Ealick SE J Biol Chem. 2004 Jan 23;279(4):2704-11. Epub 2003 Oct 28. PMID:14585832<ref>PMID:14585832</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>

</div>

<div class="pdbe-citations 1r9g" style="background-color:#fffaf0;"></div>

== References ==

<references/>

[[Category: Vibrio subtilis ehrenberg 1835]]

[[Category: Bauer, J A]]

[[Category: Begley, T P]]

[[Category: Bennett, E M]]

[[Category: Ealick, S E]]

[[Category: Triad amidotransferase]]