1s4q

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<StructureSection load='1s4q' size='340' side='right'caption='[[1s4q]], [[Resolution|resolution]] 2.16&Aring;' scene=''>
<StructureSection load='1s4q' size='340' side='right'caption='[[1s4q]], [[Resolution|resolution]] 2.16&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1s4q]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S4Q OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1S4Q FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1s4q]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S4Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1S4Q FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.16&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GMK, RV1389, MT1434, MTCY21B4.06, MB1424 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Guanylate_kinase Guanylate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.8 2.7.4.8] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1s4q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s4q OCA], [https://pdbe.org/1s4q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1s4q RCSB], [https://www.ebi.ac.uk/pdbsum/1s4q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1s4q ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1s4q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s4q OCA], [http://pdbe.org/1s4q PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1s4q RCSB], [http://www.ebi.ac.uk/pdbsum/1s4q PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1s4q ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/KGUA_MYCTU KGUA_MYCTU]] Essential for recycling GMP and indirectly, cGMP (By similarity).[HAMAP-Rule:MF_00328]
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[https://www.uniprot.org/uniprot/KGUA_MYCTU KGUA_MYCTU] Essential for recycling GMP and indirectly, cGMP (By similarity).[HAMAP-Rule:MF_00328]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Guanylate kinase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Myctu]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Chan, S]]
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[[Category: Chan S]]
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[[Category: Eisenberg, D]]
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[[Category: Eisenberg D]]
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[[Category: Perry, L J]]
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[[Category: Perry LJ]]
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[[Category: Sawaya, M R]]
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[[Category: Sawaya MR]]
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[[Category: Structural genomic]]
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[[Category: Atp:gmp-phosphotransferase]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Tbsgc]]
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[[Category: Transferase]]
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Revision as of 08:28, 1 May 2024

Crystal Structure of Guanylate Kinase from Mycobacterium tuberculosis (Rv1389)

PDB ID 1s4q

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