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1tvt

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Revision as of 06:41, 2 March 2022

STRUCTURE OF THE EQUINE INFECTIOUS ANEMIA VIRUS TAT PROTEIN

Structural highlights

1tvt is a 1 chain structure with sequence from Eiav. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Gene:	POTENTIAL (EIAV)
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Publication Abstract from PubMed

Trans-activator (Tat) proteins regulate the transcription of lentiviral DNA in the host cell genome. These RNA binding proteins participate in the life cycle of all known lentiviruses, such as the human immunodeficiency viruses (HIV) or the equine infectious anemia virus (EIAV). The consensus RNA binding motifs [the trans-activation responsive element (TAR)] of HIV-1 as well as EIAV Tat proteins are well characterized. The structure of the 75-amino acid EIAV Tat protein in solution was determined by two- and three-dimensional nuclear magnetic resonance methods and molecular dynamics calculations. The protein structure exhibits a well-defined hydrophobic core of 15 amino acids that serves as a scaffold for two flexible domains corresponding to the NH2- and COOH-terminal regions. The core region is a strictly conserved sequence region among the known Tat proteins. The structural data can be used to explain several of the observed features of Tat proteins.

Structure of the equine infectious anemia virus Tat protein.,Willbold D, Rosin-Arbesfeld R, Sticht H, Frank R, Rosch P Science. 1994 Jun 10;264(5165):1584-7. PMID:7515512^[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

↑ Willbold D, Rosin-Arbesfeld R, Sticht H, Frank R, Rosch P. Structure of the equine infectious anemia virus Tat protein. Science. 1994 Jun 10;264(5165):1584-7. PMID:7515512

1 Structural highlights
2 Evolutionary Conservation
3 Publication Abstract from PubMed
4 See Also
5 References

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1tvt"

Categories: Eiav | Large Structures | Roesch, P | Willbold, D | Transcription regulation

@@ Line 3: / Line 3: @@
 <StructureSection load='1tvt' size='340' side='right'caption='[[1tvt]], [[NMR_Ensembles_of_Models | 6 NMR models]]' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1tvt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Eiav Eiav]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TVT OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1TVT FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1tvt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Eiav Eiav]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TVT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TVT FirstGlance]. <br>
-</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">POTENTIAL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11665 EIAV])</td></tr>
+</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">POTENTIAL ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11665 EIAV])</td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1tvt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tvt OCA], [http://pdbe.org/1tvt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1tvt RCSB], [http://www.ebi.ac.uk/pdbsum/1tvt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1tvt ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tvt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tvt OCA], [https://pdbe.org/1tvt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tvt RCSB], [https://www.ebi.ac.uk/pdbsum/1tvt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tvt ProSAT]</span></td></tr>
 </table>
 == Evolutionary Conservation ==

1tvt

From Proteopedia

Revision as of 06:41, 2 March 2022

STRUCTURE OF THE EQUINE INFECTIOUS ANEMIA VIRUS TAT PROTEIN

Structural highlights

Evolutionary Conservation

Publication Abstract from PubMed

See Also

References

Contents

Proteopedia Page Contributors and Editors (what is this?)

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