6zfw
From Proteopedia
(Difference between revisions)
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<StructureSection load='6zfw' size='340' side='right'caption='[[6zfw]], [[Resolution|resolution]] 1.58Å' scene=''> | <StructureSection load='6zfw' size='340' side='right'caption='[[6zfw]], [[Resolution|resolution]] 1.58Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[6zfw]] is a 5 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[6zfw]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_cruzi Trypanosoma cruzi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ZFW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ZFW FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.58Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zfw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zfw OCA], [https://pdbe.org/6zfw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zfw RCSB], [https://www.ebi.ac.uk/pdbsum/6zfw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zfw ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/Q4D1H5_TRYCC Q4D1H5_TRYCC] Component of the PEX13-PEX14 docking complex, a translocon channel that specifically mediates the import of peroxisomal cargo proteins bound to PEX5 receptor. The PEX13-PEX14 docking complex forms a large import pore which can be opened to a diameter of about 9 nm. Mechanistically, PEX5 receptor along with cargo proteins associates with the PEX14 subunit of the PEX13-PEX14 docking complex in the cytosol, leading to the insertion of the receptor into the organelle membrane with the concomitant translocation of the cargo into the peroxisome matrix.[RuleBase:RU367032] |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Trycr]] | ||
| - | [[Category: Ostertag, M O]] | ||
| - | [[Category: Popowicz, G P]] | ||
| - | [[Category: Sattler, M]] | ||
| - | [[Category: Softley, C A]] | ||
| - | [[Category: Chagas disease]] | ||
| - | [[Category: Glycosomal import]] | ||
| - | [[Category: Peroxisome]] | ||
| - | [[Category: Protein transport]] | ||
[[Category: Trypanosoma cruzi]] | [[Category: Trypanosoma cruzi]] | ||
| + | [[Category: Ostertag MO]] | ||
| + | [[Category: Popowicz GP]] | ||
| + | [[Category: Sattler M]] | ||
| + | [[Category: Softley CA]] | ||
Current revision
X-ray structure of the soluble N-terminal domain of T. cruzi PEX-14
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