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Ubiquitin

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Line 94: Line 94:
**[[6nxl]] – hUBB<br />
**[[6nxl]] – hUBB<br />
-
**[[4zpz]], [[6qk9]] – hUBB (mutant)<br />
+
**[[4zpz]], [[6qk9]], [[5w46]] – hUBB (mutant)<br />
**[[5x3o]], [[3x3m]] – hUBB + d-ubiquitin <br />
**[[5x3o]], [[3x3m]] – hUBB + d-ubiquitin <br />
**[[3phd]] – hUBB + histone deacetylase 6
**[[3phd]] – hUBB + histone deacetylase 6
Line 109: Line 109:
**[[6fyh]] – hUBB + E3 UBB protein ligase HUWE1<br />
**[[6fyh]] – hUBB + E3 UBB protein ligase HUWE1<br />
**[[6fx4]] – hUBB (mutant) + E3 UBB protein ligase SMURF2<br />
**[[6fx4]] – hUBB (mutant) + E3 UBB protein ligase SMURF2<br />
-
**[[6hek]] – hUBB + UBB carboxyl terminal hydrolase<br />
+
**[[6hek]] – hUBB + USP<br />
**[[5mnj]] – hUBB + E3 UBB protein ligase MDM2 + UbcH5B<br />
**[[5mnj]] – hUBB + E3 UBB protein ligase MDM2 + UbcH5B<br />
**[[6hpr]] – hUBB + IAP1 + UbcH5B<br />
**[[6hpr]] – hUBB + IAP1 + UbcH5B<br />
Line 115: Line 115:
**[[5l8w]] – hUBB + WD repeat-containing protein 48 + USP12<br />
**[[5l8w]] – hUBB + WD repeat-containing protein 48 + USP12<br />
**[[5l8h]] – hUBB + WD repeat-containing protein 48 + USP46<br />
**[[5l8h]] – hUBB + WD repeat-containing protein 48 + USP46<br />
 +
**[[6dgf]] – hUBB + USP2<br />
**[[5kyf]], [[5kye]], [[5kyd]], [[5kyc]] – hUBB + USP7<br />
**[[5kyf]], [[5kye]], [[5kyd]], [[5kyc]] – hUBB + USP7<br />
 +
**[[6hei]] – hUBB + USP28<br />
**[[6ftx]] – hUBB + histones H4+H2A+H2B+H3.3C + DNA - Cryo EM<br />
**[[6ftx]] – hUBB + histones H4+H2A+H2B+H3.3C + DNA - Cryo EM<br />
 +
**[[6byh]], [[6c16]] – hUBB + Skp1 + Fbl11<br />
 +
**[[6bva]] – hUBB + Skp1 + Fbl10<br />
* Polyubiquitin-C
* Polyubiquitin-C
-
**[[5af4]], [[4xyz]] – hUBC <br />
+
**[[5af4]], [[4xyz]]. [[6k2u]] – hUBC <br />
**[[5af5]], [[5nl4]] – hUBC (mutant)<br />
**[[5af5]], [[5nl4]] – hUBC (mutant)<br />
**[[3znz]] – hUBC + otulin<br />
**[[3znz]] – hUBC + otulin<br />
Line 130: Line 134:
**[[6s53]] – hUBC + TRIM1 + UB-conjugating enzyme E2<br />
**[[6s53]] – hUBC + TRIM1 + UB-conjugating enzyme E2<br />
**[[6t7f]] – hUBC + E3 UBB protein ligase + UB-conjugating enzyme E2<br />
**[[6t7f]] – hUBC + E3 UBB protein ligase + UB-conjugating enzyme E2<br />
 +
**[[6nxk]] – hUBC + anaphase promoting complex subunit 2<br />
 +
**[[6rya]] – hUBC + Dup1<br />
 +
**[[6b7o]] – hUBC + SdeD<br />
* Ubiquitin monomer bound to protein
* Ubiquitin monomer bound to protein
Line 136: Line 143:
**[[3i3t]], [[2ibi]], [[2ayo]], [[1nbf]], [[2wdt]], [[4i6l]], [[4i6n]], [[4ig7]], [[5l8h]], [[5jtj]], [[5cvm]], [[6crn]], [[6ml1]] - hUBB+hUBB carboxyl-terminal hydrolase catalytic domain<br />
**[[3i3t]], [[2ibi]], [[2ayo]], [[1nbf]], [[2wdt]], [[4i6l]], [[4i6n]], [[4ig7]], [[5l8h]], [[5jtj]], [[5cvm]], [[6crn]], [[6ml1]] - hUBB+hUBB carboxyl-terminal hydrolase catalytic domain<br />
**[[3n3k]], [[3ifw]], [[3kvf]], [[3kw5]], [[3irt]], [[3mtn]], [[3ihp]], [[3v6c]], [[3v6e]]– hUBB (mutant)+hUBB carboxyl-terminal esterase catalytic domain<br />
**[[3n3k]], [[3ifw]], [[3kvf]], [[3kw5]], [[3irt]], [[3mtn]], [[3ihp]], [[3v6c]], [[3v6e]]– hUBB (mutant)+hUBB carboxyl-terminal esterase catalytic domain<br />
-
**[[5l8w]], [[5cvn]], [[5cvo]] – hUBB + UBB carboxy terminal hydrolase 12 + WD repeat containing protein 48<br />
+
**[[5l8w]], [[5cvn]], [[5cvo]] – hUBB + USP12 + WD repeat containing protein 48<br />
 +
**[[6cpm]] – hUBB (mutant) + USP15<br />
**[[2khw]] – hUBB+immunoglobulin G-binding protein G<br />
**[[2khw]] – hUBB+immunoglobulin G-binding protein G<br />
**[[1yx5]], [[1yx6]] - hUBB+26S proteasome non-ATPase regulatory subunit – NMR<br />
**[[1yx5]], [[1yx6]] - hUBB+26S proteasome non-ATPase regulatory subunit – NMR<br />
Line 174: Line 182:
**[[6q01]] – hUBB + TDP2<br />
**[[6q01]] – hUBB + TDP2<br />
**[[6asr]] – hUBB + REV1<br />
**[[6asr]] – hUBB + REV1<br />
 +
**[[5vzm]] – hUBB + REV1 - NMR<br />
 +
**[[5zq5]] – hUBB + SidE<br />
 +
**[[5zq4]], [[5zq6]], [[5zq7]] – hUBB + SidE + nucleotide<br />
 +
**[[6oam]] – hUBB + Dub2<br />
 +
**[[5yij]] – hUBB + SdeA<br />
 +
**[[6b7m]] – hUBB + SdeD<br />
**[[6ob1]] – hUBB + WHB - NMR<br />
**[[6ob1]] – hUBB + WHB - NMR<br />
**[[4un2]] – hUBB + Dsk2 peptide<br />
**[[4un2]] – hUBB + Dsk2 peptide<br />
**[[4msq]], [[4msm]] – hUBB + AMSH-like protease<br />
**[[4msq]], [[4msm]] – hUBB + AMSH-like protease<br />
 +
**[[5yt6]] – hUBB + Tax1 binding protein<br />
**[[6q01]] – hUBB + RPN10<br />
**[[6q01]] – hUBB + RPN10<br />
**[[5v1z]], [[5v1y]], [[6oi4]] – hUBB + RPN13 + RPN2<br />
**[[5v1z]], [[5v1y]], [[6oi4]] – hUBB + RPN13 + RPN2<br />
Line 187: Line 202:
**[[6eqi]] – hUBB + NB696 + PINK1<br />
**[[6eqi]] – hUBB + NB696 + PINK1<br />
**[[5ohv]] – hUBB + K33-specific affimer<br />
**[[5ohv]] – hUBB + K33-specific affimer<br />
-
**[[5af6]] – hUBB + TRABID<br />
 
**[[4un2]] – hUBB + Dsk2 peptide<br />
**[[4un2]] – hUBB + Dsk2 peptide<br />
**[[4msq]], [[4msm]] – hUBB + AMSH-like protease<br />
**[[4msq]], [[4msm]] – hUBB + AMSH-like protease<br />
Line 194: Line 208:
**[[4m0w]] – bUBB + replicase polyprotein<br />
**[[4m0w]] – bUBB + replicase polyprotein<br />
**[[1uzx]] – bUBB+VPS23 UEV<br />
**[[1uzx]] – bUBB+VPS23 UEV<br />
-
**[[2hd5]] - bUBB+hUBB carboxyl-terminal hydrolase catalytic domain<br />
+
**[[2hd5]] - bUBB+hUSP catalytic domain<br />
**[[3ldz]] – bUBB+signal transducing adapter molecule<br />
**[[3ldz]] – bUBB+signal transducing adapter molecule<br />
**[[1v80]], [[1v81]] – bUBB/L40 ribosomal protein fusion - NMR<br />
**[[1v80]], [[1v81]] – bUBB/L40 ribosomal protein fusion - NMR<br />

Revision as of 09:55, 2 January 2021

Human ubiquitin (green) complex with ubiquitin-conjugating enzyme E2 (deep sky blue), 3k9p

Drag the structure with the mouse to rotate

3D Structures of Ubiquitin

Updated on 02-January-2021

References

  1. ↑ Hershko A, Ciechanover A. The ubiquitin system. Annu Rev Biochem. 1998;67:425-79. PMID:9759494 doi:http://dx.doi.org/10.1146/annurev.biochem.67.1.425
  2. ↑ Paul S. Dysfunction of the ubiquitin-proteasome system in multiple disease conditions: therapeutic approaches. Bioessays. 2008 Nov;30(11-12):1172-84. doi: 10.1002/bies.20852. PMID:18937370 doi:http://dx.doi.org/10.1002/bies.20852
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