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Ubiquitin

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Line 22: Line 22:
**[[2ojr]], [[2nr2]], [[2fcq]], [[1ubi]], [[1ubq]], [[1xqq]], [[3ons]], [[4wzp]], [[5k9p]], [[4zqs]], [[5dk8]], [[4xof]], [[4xok]], [[4xol]], [[4zpz]] - hUBB - human<br />
**[[2ojr]], [[2nr2]], [[2fcq]], [[1ubi]], [[1ubq]], [[1xqq]], [[3ons]], [[4wzp]], [[5k9p]], [[4zqs]], [[5dk8]], [[4xof]], [[4xok]], [[4xol]], [[4zpz]] - hUBB - human<br />
**[[2zcb]], [[2gbj]], [[2gbk]], [[2gbm]], [[2gbn]], [[2gbr]], [[2fcm]], [[2fcn]], [[2fcs]], [[1yiw]], [[1yj1]], [[1sif]], [[1ogw]], [[4hk2]], [[4hjk]], [[4pij]], [[4pih]], [[4pig]] - hUBB (mutant)<br />
**[[2zcb]], [[2gbj]], [[2gbk]], [[2gbm]], [[2gbn]], [[2gbr]], [[2fcm]], [[2fcn]], [[2fcs]], [[1yiw]], [[1yj1]], [[1sif]], [[1ogw]], [[4hk2]], [[4hjk]], [[4pij]], [[4pih]], [[4pig]] - hUBB (mutant)<br />
-
**[[2kn5]], [[2klg]], [[2jzz]], [[2pe9]], [[2pea]], [[1g6j]], [[1d3z]], [[2kox]], [[2ld9]], [[2k25]], [[5ujl]] – hUBB – NMR<br />
+
**[[2kn5]], [[2klg]], [[2jzz]], [[2pe9]], [[2pea]], [[1g6j]], [[1d3z]], [[2kox]], [[2ld9]], [[2k25]], [[5ujl]], [[6v5d]] – hUBB – NMR<br />
-
**[[1c3t]], [[1ud7]], [[2mi8]], [[2rsu]], [[2ru6]] - hUBB (mutant) - NMR<br />
+
**[[1c3t]], [[1ud7]], [[2mi8]], [[2rsu]], [[2ru6]], [[6k4i]] - hUBB (mutant) - NMR<br />
**[[2m0x]] - hUBB - engineered – NMR<br />
**[[2m0x]] - hUBB - engineered – NMR<br />
**[[6gf1]] - hUBB D<br />
**[[6gf1]] - hUBB D<br />
Line 121: Line 121:
**[[6byh]], [[6c16]] – hUBB + Skp1 + Fbl11<br />
**[[6byh]], [[6c16]] – hUBB + Skp1 + Fbl11<br />
**[[6bva]] – hUBB + Skp1 + Fbl10<br />
**[[6bva]] – hUBB + Skp1 + Fbl10<br />
 +
**[[6a6i]] – hUBB + Cockayne syndrome group B protein <br />
* Polyubiquitin-C
* Polyubiquitin-C
Line 141: Line 142:
**[[3ofi]] – hUBB+insulin protease
**[[3ofi]] – hUBB+insulin protease
-
**[[3i3t]], [[2ibi]], [[2ayo]], [[1nbf]], [[2wdt]], [[4i6l]], [[4i6n]], [[4ig7]], [[5l8h]], [[5jtj]], [[5cvm]], [[6crn]], [[6ml1]] - hUBB+hUBB carboxyl-terminal hydrolase catalytic domain<br />
+
**[[3i3t]], [[2ibi]], [[2ayo]], [[1nbf]], [[2wdt]], [[4i6l]], [[4i6n]], [[4ig7]], [[5l8h]], [[5jtj]], [[5cvm]], [[6crn]], [[6ml1]] - hUBB+ USP catalytic domain<br />
**[[3n3k]], [[3ifw]], [[3kvf]], [[3kw5]], [[3irt]], [[3mtn]], [[3ihp]], [[3v6c]], [[3v6e]]– hUBB (mutant)+hUBB carboxyl-terminal esterase catalytic domain<br />
**[[3n3k]], [[3ifw]], [[3kvf]], [[3kw5]], [[3irt]], [[3mtn]], [[3ihp]], [[3v6c]], [[3v6e]]– hUBB (mutant)+hUBB carboxyl-terminal esterase catalytic domain<br />
-
**[[5l8w]], [[5cvn]], [[5cvo]] – hUBB + USP12 + WD repeat containing protein 48<br />
 
**[[6cpm]] – hUBB (mutant) + USP15<br />
**[[6cpm]] – hUBB (mutant) + USP15<br />
**[[2khw]] – hUBB+immunoglobulin G-binding protein G<br />
**[[2khw]] – hUBB+immunoglobulin G-binding protein G<br />
Line 170: Line 170:
**[[4zfr]], [[4zft]] – hUBB + SST2<br />
**[[4zfr]], [[4zft]] – hUBB + SST2<br />
**[[2j7q]] – hUBB + McmV tegument protein<br />
**[[2j7q]] – hUBB + McmV tegument protein<br />
-
**[[4dhj]], [[4dhz]] – hUBB (mutant) + UBB thiolesterase + UBB aldehyde <br />
 
**[[3rul]] – hUBB + dalvancin<br />
**[[3rul]] – hUBB + dalvancin<br />
**[[3vfk]] – hUBB + monodechloro-teicoplanin <br />
**[[3vfk]] – hUBB + monodechloro-teicoplanin <br />
Line 180: Line 179:
**[[4jio]] – hUBB + yBRO1<br />
**[[4jio]] – hUBB + yBRO1<br />
**[[5af6]] – hUBB + TRABID<br />
**[[5af6]] – hUBB + TRABID<br />
-
**[[6q01]] – hUBB + TDP2<br />
+
**[[6q01]], [[6q00]] – hUBB + TDP2<br />
**[[6asr]] – hUBB + REV1<br />
**[[6asr]] – hUBB + REV1<br />
**[[5vzm]] – hUBB + REV1 - NMR<br />
**[[5vzm]] – hUBB + REV1 - NMR<br />
**[[5zq5]] – hUBB + SidE<br />
**[[5zq5]] – hUBB + SidE<br />
-
**[[5zq4]], [[5zq6]], [[5zq7]] – hUBB + SidE + nucleotide<br />
 
**[[6oam]] – hUBB + Dub2<br />
**[[6oam]] – hUBB + Dub2<br />
**[[5yij]] – hUBB + SdeA<br />
**[[5yij]] – hUBB + SdeA<br />
Line 193: Line 191:
**[[5yt6]] – hUBB + Tax1 binding protein<br />
**[[5yt6]] – hUBB + Tax1 binding protein<br />
**[[6q01]] – hUBB + RPN10<br />
**[[6q01]] – hUBB + RPN10<br />
-
**[[5v1z]], [[5v1y]], [[6oi4]] – hUBB + RPN13 + RPN2<br />
 
**[[5jp3]] – hUBB + xanthomonas outer protein<br />
**[[5jp3]] – hUBB + xanthomonas outer protein<br />
**[[5lrw]] – hUBB (mutant)+ OUT domain containing protein 7B<br />
**[[5lrw]] – hUBB (mutant)+ OUT domain containing protein 7B<br />
Line 225: Line 222:
**[[1otr]] – yUBB+CUE2<br />
**[[1otr]] – yUBB+CUE2<br />
**[[2l00]] – yUBB + Zfand5<br />
**[[2l00]] – yUBB + Zfand5<br />
 +
 +
* Ubiquitin binary complex with protein
 +
 +
**[[5l8w]], [[5cvn]], [[5cvo]] – hUBB + USP12 + WD repeat containing protein 48<br />
 +
**[[4dhj]], [[4dhz]] – hUBB (mutant) + UBB thiolesterase + UBB aldehyde <br />
 +
**[[5zq4]], [[5zq6]], [[5zq7]] – hUBB + SidE + nucleotide<br />
 +
**[[5v1z]], [[5v1y]], [[6oi4]] – hUBB + RPN13 + RPN2<br />
 +
**[[6eqi]] – hUBB + Nb696 + PINK1<br />
**[[6oaa]], [[6oa9]] – yUBB + Npl4 + cdc48 - Cryo EM<br />
**[[6oaa]], [[6oa9]] – yUBB + Npl4 + cdc48 - Cryo EM<br />
 +
**[[5wvo]] – hUBB + Npl4 + cdc48 - Cryo EM<br />
* Ubiquitin complex with ubiquitination enzymes
* Ubiquitin complex with ubiquitination enzymes

Revision as of 07:02, 3 January 2021

Human ubiquitin (green) complex with ubiquitin-conjugating enzyme E2 (deep sky blue), 3k9p

Drag the structure with the mouse to rotate

3D Structures of Ubiquitin

Updated on 03-January-2021

References

  1. Hershko A, Ciechanover A. The ubiquitin system. Annu Rev Biochem. 1998;67:425-79. PMID:9759494 doi:http://dx.doi.org/10.1146/annurev.biochem.67.1.425
  2. Paul S. Dysfunction of the ubiquitin-proteasome system in multiple disease conditions: therapeutic approaches. Bioessays. 2008 Nov;30(11-12):1172-84. doi: 10.1002/bies.20852. PMID:18937370 doi:http://dx.doi.org/10.1002/bies.20852
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