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1wxa
From Proteopedia
(Difference between revisions)
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<StructureSection load='1wxa' size='340' side='right'caption='[[1wxa]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | <StructureSection load='1wxa' size='340' side='right'caption='[[1wxa]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1wxa]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1wxa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WXA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WXA FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RIKEN cDNA 4932441D06 ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RIKEN cDNA 4932441D06 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wxa OCA], [https://pdbe.org/1wxa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wxa RCSB], [https://www.ebi.ac.uk/pdbsum/1wxa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wxa ProSAT], [https://www.topsan.org/Proteins/RSGI/1wxa TOPSAN]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/AFAD_MOUSE AFAD_MOUSE]] Belongs to an adhesion system, probably together with the E-cadherin-catenin system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). Nectin- and actin-filament-binding protein that connects nectin to the actin cytoskeleton. May play a key role in the organization of epithelial structures of the embryonic ectoderm.<ref>PMID:10477764</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 07:00, 2 March 2022
Solution Structure of Ras-binding Domain in Mouse AF-6 Protein
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Categories: Large Structures | Lk3 transgenic mice | Inoue, M | Kigawa, T | Koshiba, S | Structural genomic | Tomizawa, T | Yokoyama, S | Zhao, C | Af-6 protein | Afadin | Cell adhesion | National project on protein structural and functional analyse | Nppsfa | Ras-binding domain | Rsgi | Ubiquitin-like fold
