This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1wyr

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 3: Line 3:
<StructureSection load='1wyr' size='340' side='right'caption='[[1wyr]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='1wyr' size='340' side='right'caption='[[1wyr]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[1wyr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WYR OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1WYR FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[1wyr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WYR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WYR FirstGlance]. <br>
-
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ARHGEF6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ARHGEF6 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1wyr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wyr OCA], [http://pdbe.org/1wyr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1wyr RCSB], [http://www.ebi.ac.uk/pdbsum/1wyr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1wyr ProSAT], [http://www.topsan.org/Proteins/RSGI/1wyr TOPSAN]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wyr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wyr OCA], [https://pdbe.org/1wyr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wyr RCSB], [https://www.ebi.ac.uk/pdbsum/1wyr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wyr ProSAT], [https://www.topsan.org/Proteins/RSGI/1wyr TOPSAN]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
-
[[http://www.uniprot.org/uniprot/ARHG6_HUMAN ARHG6_HUMAN]] Defects in ARHGEF6 are the cause of mental retardation X-linked type 46 (MRX46) [MIM:[http://omim.org/entry/300436 300436]]. Mental retardation is a mental disorder characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs.<ref>PMID:11017088</ref>
+
[[https://www.uniprot.org/uniprot/ARHG6_HUMAN ARHG6_HUMAN]] Defects in ARHGEF6 are the cause of mental retardation X-linked type 46 (MRX46) [MIM:[https://omim.org/entry/300436 300436]]. Mental retardation is a mental disorder characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs.<ref>PMID:11017088</ref>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/ARHG6_HUMAN ARHG6_HUMAN]] Acts as a RAC1 guanine nucleotide exchange factor (GEF).
+
[[https://www.uniprot.org/uniprot/ARHG6_HUMAN ARHG6_HUMAN]] Acts as a RAC1 guanine nucleotide exchange factor (GEF).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 07:01, 2 March 2022

Solution structure of the CH domain of human Rho guanine nucleotide exchange factor 6

PDB ID 1wyr

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1wyr"
Personal tools