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1x5m
From Proteopedia
(Difference between revisions)
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<StructureSection load='1x5m' size='340' side='right'caption='[[1x5m]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | <StructureSection load='1x5m' size='340' side='right'caption='[[1x5m]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1x5m]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1x5m]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X5M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1X5M FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CACYBP, S100A6BP, SIP ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CACYBP, S100A6BP, SIP ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1x5m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x5m OCA], [https://pdbe.org/1x5m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1x5m RCSB], [https://www.ebi.ac.uk/pdbsum/1x5m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1x5m ProSAT], [https://www.topsan.org/Proteins/RSGI/1x5m TOPSAN]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/CYBP_HUMAN CYBP_HUMAN]] May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1).<ref>PMID:16085652</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 07:05, 2 March 2022
Solution structure of the core domain of calcyclin binding protein; siah-interacting protein (SIP)
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Categories: Human | Large Structures | Hayashi, F | Nagashima, T | Qin, X R | Structural genomic | Yokoyama, S | Apoptosis | Calcyclin-binding protein/siah-interacting protein/s100a6-binding protein | Cs domain | National project on protein structural and functional analyse | Nppsfa | Rsgi | Signaling protein
