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1xa8

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Current revision (08:06, 25 October 2023) (edit) (undo)
 
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<StructureSection load='1xa8' size='340' side='right'caption='[[1xa8]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
<StructureSection load='1xa8' size='340' side='right'caption='[[1xa8]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1xa8]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_17741 Atcc 17741]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XA8 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1XA8 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1xa8]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Paracoccus_denitrificans Paracoccus denitrificans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XA8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XA8 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1x6m|1x6m]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gfa ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=266 ATCC 17741])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xa8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xa8 OCA], [https://pdbe.org/1xa8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xa8 RCSB], [https://www.ebi.ac.uk/pdbsum/1xa8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xa8 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1xa8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xa8 OCA], [http://pdbe.org/1xa8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1xa8 RCSB], [http://www.ebi.ac.uk/pdbsum/1xa8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1xa8 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/GFA_PARDE GFA_PARDE]] Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione.<ref>PMID:11741920</ref>
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[https://www.uniprot.org/uniprot/GFA_PARDE GFA_PARDE] Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione.<ref>PMID:11741920</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 17741]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Becker, S]]
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[[Category: Paracoccus denitrificans]]
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[[Category: Griesinger, C]]
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[[Category: Becker S]]
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[[Category: Neculai, A M]]
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[[Category: Griesinger C]]
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[[Category: Neculai, D]]
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[[Category: Neculai AM]]
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[[Category: Vorholt, J A]]
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[[Category: Neculai D]]
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[[Category: Formaldehyde]]
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[[Category: Vorholt JA]]
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[[Category: Glutathione]]
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[[Category: Lyase]]
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[[Category: S-s bond]]
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Current revision

Crystal Structure Analysis of Glutathione-dependent formaldehyde-activating enzyme (Gfa)

PDB ID 1xa8

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